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Bioss


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Numéro de catalogue: (BOSSBS-1420R)

Fournisseur:  Bioss
Description:   Anti-NCOR2 Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0787R)

Fournisseur:  Bioss
Description:   Anti-IFNB1 Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1369R)

Fournisseur:  Bioss
Description:   Anti-MAP2 Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1329R)

Fournisseur:  Bioss
Description:   Anti-ZO1 Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1451R)

Fournisseur:  Bioss
Description:   Anti-PAFAH/Lp-PLA2 Rabbit Polyclonal Antibody
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Anti-Measles virus fusion protein Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-3440R)

Fournisseur:  Bioss
Description:   Anti-TBK1 Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1447R)

Fournisseur:  Bioss
Description:   Anti-HIF 2 alpha Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4753R)

Fournisseur:  Bioss
Description:   Anti-NAPSA Rabbit Polyclonal Antibody
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2934R-A555)

Fournisseur:  Bioss
Description:   C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2 (PubMed:837664, PubMed:29953, PubMed:959512, PubMed:1432298, PubMed:15833747, PubMed:16333141, PubMed:1961575).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0211R-CY3)

Fournisseur:  Bioss
Description:   Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12889R-A488)

Fournisseur:  Bioss
Description:   The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11733R-A488)

Fournisseur:  Bioss
Description:   Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8353R-A555)

Fournisseur:  Bioss
Description:   Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme. The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex. The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, thereby targeting that substrate for degradation. A wide range of enzymes facilitate this proteolytic ubiquitin pathway, one of which is UBE2E2 (also known as UBCH8 in human), which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, thereby playing an important role in protein degradation.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8107R-A555)

Fournisseur:  Bioss
Description:   CCDC129
UOM:  1 * 100 µl
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