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Bioss
Numéro de catalogue:
(BOSSBS-5744R-A350)
Fournisseur:
Bioss
Description:
CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers.The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2010R-A350)
Fournisseur:
Bioss
Description:
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13157R-CY5)
Fournisseur:
Bioss
Description:
Src is the human homolog of the v-Src gene of the rous sarcoma virus, also designated avian sarcoma virus or ASV. Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. The Src family, which has common structural motifs, is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family ki-nases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain, which are involved in modular association and activation, respectively. Src-family kinases, which are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Fgr is a human non-receptor tyrosine kinase family member that was discovered by using a probe toward the v-Fgr portion of the cell-derived domain of Gardner-Rasheed feline sarcoma virus. The human c-Fgr gene encodes a 529 amino acid protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5744R-CY3)
Fournisseur:
Bioss
Description:
CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers.The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5744R-A647)
Fournisseur:
Bioss
Description:
CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers.The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0408R-CY5.5)
Fournisseur:
Bioss
Description:
Heamachrome
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0300R-A647)
Fournisseur:
Bioss
Description:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0300R-A488)
Fournisseur:
Bioss
Description:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2010R-A647)
Fournisseur:
Bioss
Description:
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2955R-CY5)
Fournisseur:
Bioss
Description:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2959R-CY3)
Fournisseur:
Bioss
Description:
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2955R-HRP)
Fournisseur:
Bioss
Description:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1030R-HRP)
Fournisseur:
Bioss
Description:
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4908R-CY7)
Fournisseur:
Bioss
Description:
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4908R-FITC)
Fournisseur:
Bioss
Description:
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8571R-CY7)
Fournisseur:
Bioss
Description:
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM:
1 * 100 µl
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