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Bioss
Numéro de catalogue:
(BOSSBS-6160R-A350)
Fournisseur:
Bioss
Description:
VAV2 is a ubiquitously expressed structural homolog of the VAV protooncogene that is expressed preferentially in hematopoetic cells. Both proteins are comprised of a Dbl homology (DH) domain with guanosine nucleotide exchange (GEF) activity exclusively directed towards Rho/Rac GTPases, a pleckstrin homology (PH) domain, a calponin-homology (CH) region, an acidic domain (AD) a zinc finger butterfly motif, two SH3 regions and one SH2 domain. GEF activity of RhoA family G proteins is induced by tyrosine phosphorylation in wild type VAV2, and is constitutively activated in N terminus deleted oncogene forms. Constitutive expression of a VAV2 oncoprotein may result in morphological alterations including highly enlarged cells in which karyokinesis and cytokinesis frequently are uncoupled.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6192R-A750)
Fournisseur:
Bioss
Description:
Enhances neuronal dendrite outgrowth.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2448R-CY3)
Fournisseur:
Bioss
Description:
This protein is part of the THO complex (THOC). The THO complex is recruited to transcribed genes and travels with the RNA polymerase during elongation. It may physically link proteins that function in transcription and in RNA export and RNA processing.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10366R-FITC)
Fournisseur:
Bioss
Description:
Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1025R-A680)
Fournisseur:
Bioss
Description:
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6811R-CY7)
Fournisseur:
Bioss
Description:
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11652R-A647)
Fournisseur:
Bioss
Description:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6746R-A680)
Fournisseur:
Bioss
Description:
TULP2 is a member of a family of tubby-like (TULP) proteins which share a conserved C terminal region of approximately 200 amino acid residues. It is strongly expressed in testis and is expressed in the retina. It is also expressed in cancer cell lines.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6746R-A750)
Fournisseur:
Bioss
Description:
TULP2 is a member of a family of tubby-like (TULP) proteins which share a conserved C terminal region of approximately 200 amino acid residues. It is strongly expressed in testis and is expressed in the retina. It is also expressed in cancer cell lines.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10228R-CY3)
Fournisseur:
Bioss
Description:
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7639R-A647)
Fournisseur:
Bioss
Description:
SLC14A1 is one of two major mammalian urea transporters, which play a critical role in the urine-concentrating mechanism. Their abundance is regulated by vasopressin, glucocorticoids, and mineralocorticoids. These regulatory mechanisms may be important in disease states such as diabetes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2010R-HRP)
Fournisseur:
Bioss
Description:
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8013R-CY7)
Fournisseur:
Bioss
Description:
CHORDC3 is a muscle-specific protein that interacts with the Integrin 1 cytoplasmic domain, in the hypertrophic response to mechanical overload.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8013R-A750)
Fournisseur:
Bioss
Description:
CHORDC3 is a muscle-specific protein that interacts with the Integrin 1 cytoplasmic domain, in the hypertrophic response to mechanical overload.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3857R-A647)
Fournisseur:
Bioss
Description:
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8013R-CY5.5)
Fournisseur:
Bioss
Description:
CHORDC3 is a muscle-specific protein that interacts with the Integrin 1 cytoplasmic domain, in the hypertrophic response to mechanical overload.
UOM:
1 * 100 µl
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