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ProSci Inc.
Numéro de catalogue:
(PRSI10-169)
Fournisseur:
ProSci Inc.
Description:
Anti-Tarvacin ch3G4 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-197)
Fournisseur:
ProSci Inc.
Description:
The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDa type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI76-206)
Fournisseur:
ProSci Inc.
Description:
The MEL-14 monoclonal antibody specifically reacts with L- selectin (CD62L), a receptor with lectin-like and Epidermal Growth Factor-like domains. The weight of the CD62L molecules depend on their origin: 74 kDa (on lymphocytes) or 95 kDa (on neutrophils).In the Mouseorganism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils. The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins (MadCAM-1, GLYCAM-1, and CD 34). It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes.
UOM:
1 * 0,025 mg
New Product
Numéro de catalogue:
(PRSI15-160)
Fournisseur:
ProSci Inc.
Description:
Anti-RND1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI56-148)
Fournisseur:
ProSci Inc.
Description:
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-152)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-143)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-139)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-150)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI18-684)
Fournisseur:
ProSci Inc.
Description:
Anti-HNMT Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI19-825)
Fournisseur:
ProSci Inc.
Description:
Anti-CD14 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI19-837)
Fournisseur:
ProSci Inc.
Description:
Anti-TCN2 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI19-826)
Fournisseur:
ProSci Inc.
Description:
Anti-CDC7 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI14-829)
Fournisseur:
ProSci Inc.
Description:
Anti-SLC5A11 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI14-846)
Fournisseur:
ProSci Inc.
Description:
Anti-OSBPL10 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI14-819)
Fournisseur:
ProSci Inc.
Description:
Anti-DNASE1L1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
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