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ProSci Inc.


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Numéro de catalogue: (PRSI61-243)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI56-275)

Fournisseur:  ProSci Inc.
Description:   Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI56-271)

Fournisseur:  ProSci Inc.
Description:   The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI56-261)

Fournisseur:  ProSci Inc.
Description:   This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI61-180)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI56-334)

Fournisseur:  ProSci Inc.
Description:   Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI61-272)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI61-289)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI56-346)

Fournisseur:  ProSci Inc.
Description:   This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI56-354)

Fournisseur:  ProSci Inc.
Description:   This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI61-281)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI56-357)

Fournisseur:  ProSci Inc.
Description:   Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI61-337)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:1000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI61-347)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI61-346)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
Numéro de catalogue: (PRSI61-330)

Fournisseur:  ProSci Inc.
Description:   For WB starting dilution is: 1:2000.
UOM:  1 * 200 µl
New Product
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