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J.T.Baker® Cell Lysis Solution & Endonuclease

Perfectly paired to optimize your harvest process sustainably

Readily biodegradable and REACH compliant J.T.Baker® products offer a scalable and sustainable clarification process. Better together, these highly effective and ready-to-use reagents minimize process challenges, so you can scale up your process without compromising performance excellence.

Avantor’s innovative J.T.Baker® Cell Lysis Solution and Endonuclease work better together to create a sustainable scale-up process — maintaining current good manufacturing practice (cGMP) quality and regulatory compliance.

Sustainable

Get the same cell lysis efficiency as Triton X-100, without the ecotoxicity concerns or potential regulatory bottlenecks.

Flexible

Highly concentrated and ready to use, these products offer adaptable storage temperatures, require less reagent volume and minimal prep time.

Scalable

Available in a wide range of size options at cGMP grade for enhanced quality, convenience, supply security and easy scale-up.

Quality

These compatible products offer the confidence you need to harvest high quality viral vector and clarify impurities without loss of viral titer.

Ready to optimize your harvest process sustainably?

See the research behind an effective cell lysis alternative that is biodegradable, requires no prep or refrigeration, and has no impact on viral vector integrity.

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Ready to scale up your gene therapy development?

Choose the easier, safer and more efficient route for harvest and clarification of your viral vector. As part of a full range of modular and scalable solutions from Avantor, you get consistent quality, supply chain security and regulatory documentation support to help fast-track gene therapy development.

    Scaling up the harvest process while preserving what matters

    There is a critical need to remove Triton™ X-100 from the cell lysis step for manufacturing. This white paper illustrates how J.T.Baker® Cell Lysis Solution provides a sustainable, scalable alternative that shows relatively equivalent performance across a range of process conditions and offers ease of use benefits.

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    Free sample: try before you buy

    We are so confident in the quality and performance of these compatible products that we’re offering a free sample of each for a limited time. Leverage the high concentration formulation that reclaims space in the bioreactor with reduced viscosity and foam generation and achieves cost, time and labor savings.

    Get My Sample