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Anticorps
Numéro de catalogue:
(BNUM0636-50)
Fournisseur:
Biotium
Description:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
UOM:
1 * 50 µl
Fournisseur:
Biotium
Description:
This MAb recognizes a 60 kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.
Numéro de catalogue:
(BOSSBS-4920R-HRP)
Fournisseur:
Bioss
Description:
K88-K99 minor fimbrial subunit, plays an essential role in the biogenesis of the K99 fimbriae. required at some step in the initiation and/or elongation of the K99 fimbriae.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12098R-A555)
Fournisseur:
Bioss
Description:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. As one of the four major proteins of the NMDA receptor ion channel, GRINA (Glutamate [NMDA] receptor-associated protein 1), also designated NMDA receptor glutamate-binding subunit or putative MAPK-activating protein PM02, is a 371 amino acid multi-pass transmembrane protein. Due to the chromosomal location of the gene encoding GRINA, studies have linked possible GRINA involvement with a form of idiopathic generalized epilepsy.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11428R-CY7)
Fournisseur:
Bioss
Description:
Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3767R-CY5)
Fournisseur:
Bioss
Description:
Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4920R-A680)
Fournisseur:
Bioss
Description:
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0,5 to 1,5 micrometers and numbering 100 to 300 per cell, enable bacteria to colonise the epithelium of specific host organs. FanC is the main component of the K99 fimbriae.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12098R-A680)
Fournisseur:
Bioss
Description:
Potential apoptotic regulator.
UOM:
1 * 100 µl
Fournisseur:
Biotium
Description:
This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.
Numéro de catalogue:
(BWRLBS3486)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to amino acids 31-80 of Human IFN-gamma.
UOM:
1 * 1 EA
Numéro de catalogue:
(BWRLBS3474)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to amino acids 111-160 of Human CD63.
UOM:
1 * 1 EA
Numéro de catalogue:
(BWRLBS1951)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to the N-terminus of Human PITSLRE.
UOM:
1 * 1 EA
Numéro de catalogue:
(BWRLBS3477)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to amino acids 220-270 of Human AQP5.
UOM:
1 * 1 EA
Numéro de catalogue:
(USBIC2069-50F)
Fournisseur:
US Biological
Description:
Anti-CTNNB1 Rabbit Monoclonal Antibody [clone: 10E12]
UOM:
1 * 100 µl
Numéro de catalogue:
(USBIB1087-07-FITC)
Fournisseur:
US Biological
Description:
Anti-BGLF4 Rabbit Polyclonal Antibody (FITC (Fluorescein))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIC2069-47G)
Fournisseur:
US Biological
Description:
Anti-CTNNB1 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
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