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Anticorps
Numéro de catalogue:
(ORIGTA303105)
Fournisseur:
OriGene
Description:
Anti-EXOC7 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Fournisseur:
Tonbo Biosciences
Description:
The N418 antibody reacts with mouse CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.
Fournisseur:
Tonbo Biosciences
Description:
The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB and CD45RO.
Fournisseur:
Tonbo Biosciences
Description:
The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
Fournisseur:
Tonbo Biosciences
Description:
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).
Fournisseur:
Biotium
Description:
This product is prepared by labeling highly cross-adsorbed donkey anti-rat IgG (H+L) with CF™405S. CF™405S is a blue fluorescent dye with an absorption peak wavelength that nearly coincides with the 405 nm blue diode laser line. In addition, the emission peak wavelength of the dye well centers within the blue detection window of BD flow cytometers. As a result, flow cytometry analysis using CF™405S dye results in much brighter signal than that using Alexa Fluor® 405. To minimize cross-reactivity, the antibody has been adsorbed against bovine, chicken, goat, guinea pig, Syrian hamster, horse, human, mouse, rabbit, and sheep serum proteins .
Alexa Fluor® is a registered trademark of Thermo Fisher Scientific.
Fournisseur:
Tonbo Biosciences
Description:
The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
Numéro de catalogue:
(PRSI36-138)
Fournisseur:
ProSci Inc.
Description:
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
UOM:
1 * 1 EA
Numéro de catalogue:
(IMMRIR1511)
Fournisseur:
ImmunoReagents
Description:
ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy. Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.
UOM:
1 * 1 mg
Numéro de catalogue:
(IMMRIR1506)
Fournisseur:
ImmunoReagents
Description:
TRITC (Tetramethylrhodamine isothiocyanate) is a popular rhodamine derivative pink in Colour but emits a red-orange Colour upon Emission at 580 nm. TRITC is frequently paired with FITC in double labeling experiments and conjugated antibodies are often used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. These conjugates are best excited with the 532 nm spectral line of the He-Ne laser and are also recommended as a second Colour detection reagent in in situ hybridization applications. (Excitation/Emission = 555 nm/580 nm Emission Colour = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, DyLight 550).
UOM:
1 * 0,5 mg
Numéro de catalogue:
(IMMRIR1540)
Fournisseur:
ImmunoReagents
Description:
TRITC (Tetramethylrhodamine isothiocyanate) is a popular rhodamine derivative pink in color but emits a red-orange color upon Emission at 580nm. TRITC is frequently paired with FITC in double labeling experiments and conjugated antibodies are often used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. These conjugates are best excited with the 532 nm spectral line of the He-Ne laser and are also recommended as a second color detection reagent in in situ hybridization applications. (Excitation/Emission = 555 nm / 580 nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, DyLight 550).
UOM:
1 * 1 mg
Numéro de catalogue:
(IMMRIR1216)
Fournisseur:
ImmunoReagents
Description:
The ImmunoReagents' DyLight® 350 conjugates are a derivative of AMCA (Aminomethylcoumarine acetate), which a blue fluorescent dye commonly is used as a contrasting dye for double- and triple-labeling used in a wide array of applications. The UV-excitable DyLight® 350 has spectral properties that are very similar to those displayed by AMCA, including identical excitation wavelengths and a large stokes shift. The emission wavelength of DyLight® 350 has a 10-nm blue shift over AMCA, though, that provides an advantage in multiplexing with green fluorophores. (Excitation/Emission = 353 nm/432 nm Emission Colour = Blue (Similar Dyes: Alexa Fluor 350, AMCA).
UOM:
1 * 1 mg
Numéro de catalogue:
(IMMRIR1214)
Fournisseur:
ImmunoReagents
Description:
The ImmunoReagents' DyLight® 350 conjugates are a derivative of AMCA (Aminomethylcoumarine acetate), which a blue fluorescent dye commonly is used as a contrasting dye for double- and triple-labeling used in a wide array of applications. The UV-excitable DyLight® 350 has spectral properties that are very similar to those displayed by AMCA, including identical excitation wavelengths and a large stokes shift. The emission wavelength of DyLight® 350 has a 10-nm blue shift over AMCA, though, that provides an advantage in multiplexing with green fluorophores. (Excitation/Emission = 353 nm/432 nm Emission Colour = Blue (Similar Dyes: Alexa Fluor 350, AMCA).
UOM:
1 * 1 mg
Numéro de catalogue:
(IMMRIR1218)
Fournisseur:
ImmunoReagents
Description:
The ImmunoReagents' DyLight® 594 conjugates generate red fluorescence and shows wide excitation wavelength separation from green fluorophores for multi-Colour applications with reduced bleedthrough. The physical characteristics of DyLight® 594 are comparable to other 594 dyes. DyLight® 594 is available for use in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 593 nm/618 nm Emission Colour = Red (Similar Dyes: Alexa Fluor 594, Texas Red).
UOM:
1 * 1 mg
Numéro de catalogue:
(IMMRIR1514)
Fournisseur:
ImmunoReagents
Description:
ImmunoReagents Biotinylated antibody conjugates are widely used due to their ability to enhance antibody signal in most immunoassays. Biotinylated secondary antibodies are used in most immunoassay formats (i.e., ELISA, Immunohistochemistry (IHC), and Western blotting). While Biotinylated antibodies by themselves do not produce a signal that can be visualized, biotin has a high affinity and specificity to Streptavidin/Avidin. Using ImmunoReagents’ streptavidin conjugates with biotinylated antibodies results in signal amplification.
UOM:
1 * 1 mg
Numéro de catalogue:
(PRSI36-183)
Fournisseur:
ProSci Inc.
Description:
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
UOM:
1 * 1 EA
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