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Anticorps
Numéro de catalogue:
(BOSSBS-0430R-CY5)
Fournisseur:
Bioss
Description:
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1794R-A647)
Fournisseur:
Bioss
Description:
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13500R-CY3)
Fournisseur:
Bioss
Description:
GPATCH3
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13500R-A555)
Fournisseur:
Bioss
Description:
GPATCH3
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6119R-A555)
Fournisseur:
Bioss
Description:
May be involved in the regulation of cellular proliferation and/or differentiation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2487R-CY5.5)
Fournisseur:
Bioss
Description:
May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0559R-FITC)
Fournisseur:
Bioss
Description:
CDK5 is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression.CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2433R-A555)
Fournisseur:
Bioss
Description:
Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0621R-CY5.5)
Fournisseur:
Bioss
Description:
Centromeric histone H3-like protein-2
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2510R-A750)
Fournisseur:
Bioss
Description:
ZNF217 (Zinc-finger protein 217) is a Kruppel-like zinc-finger protein which functions as a transcriptional repressor protein and forms a complex with a number of proteins including CoREST, BHC110/LSD1, HDAC2 and CtBP1. ZNF217 has been shown to repress E-cadherin promoter activity. ZNF217 is overexpressed in a number of cancers including breast and ovarian. ZNF217 and its associated proteins have been implicated in a novel pathway that is involved in cancer progression.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5830R-CY5.5)
Fournisseur:
Bioss
Description:
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7997R-CY5.5)
Fournisseur:
Bioss
Description:
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3851R-A647)
Fournisseur:
Bioss
Description:
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15209R-FITC)
Fournisseur:
Bioss
Description:
C5orf52
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3336R-FITC)
Fournisseur:
Bioss
Description:
IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV), measles virus (MV) and herpes simplex virus 1 (HHV-1). Inhibits viral replication via phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (EIF2S1), this phosphorylation impairs the recycling of EIF2S1 between successive rounds of initiation leading to inhibition of translation which eventually results in shutdown of cellular and viral protein synthesis. Also phosphorylates other substrates including p53/TP53, PPP2R5A, DHX9, ILF3, IRS1 and the HHV-1 viral protein US11. In addition to serine/threonine-protein kinase activity, also has tyrosine-protein kinase activity and phosphorylates CDK1 at 'Tyr-4' upon DNA damage, facilitating its ubiquitination and proteosomal degradation. Either as an adapter protein and/or via its kinase activity, can regulate various signaling pathways (p38 MAP kinase, NF-kappa-B and insulin signaling pathways) and transcription factors (JUN, STAT1, STAT3, IRF1, ATF3) involved in the expression of genes encoding proinflammatory cytokines and IFNs. Activates the NF-kappa-B pathway via interaction with IKBKB and TRAF family of proteins and activates the p38 MAP kinase pathway via interaction with MAP2K6. Can act as both a positive and negative regulator of the insulin signaling pathway (ISP). Negatively regulates ISP by inducing the inhibitory phosphorylation of insulin receptor substrate 1 (IRS1) at 'Ser-312' and positively regulates ISP via phosphorylation of PPP2R5A which activates FOXO1, which in turn up-regulates the expression of insulin receptor substrate 2 (IRS2).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11389R-A680)
Fournisseur:
Bioss
Description:
This protein functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala) (by similarity). There are 2 isoforms produced by alternative splicing.
UOM:
1 * 100 µl
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