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Fournisseur:  WATERS
Description:   Atlantis T3 columns are universal, silica based, reversed phase C18 columns that provide balanced retention of polar and hydrophobic molecules and useful for developing separations of polar and non-polar compounds.
Numéro de catalogue: (PRSI96-236)

Fournisseur:  ProSci Inc.
Description:   Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalisation and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression.
UOM:  1 * 1 EA
Fournisseur:  Thermo Fisher Scientific
Description:   Morpholine 99+% ACS
Fournisseur:  Thermo Fisher Scientific
Description:   Potassium cyanure 97% ACS
Fournisseur:  Thermo Fisher Scientific
Description:   Potassium chlorate 99+% ACS
Fournisseur:  Honeywell Chemicals
Description:   ACS GENERAL USE SOLVENTS
Fournisseur:  Thermo Fisher Scientific
Description:   Acide hydrobromique ∼48% dans l'eau ACS
Numéro de catalogue: (PRSI27-746)

Fournisseur:  ProSci Inc.
Description:   RNF130 contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-645)

Fournisseur:  ProSci Inc.
Description:   Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency
UOM:  1 * 1 EA

Fournisseur:  ProSci Inc.
Description:   The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450 nm.
UOM:  1 * 0,025 mg
New Product
Numéro de catalogue: (PRSI6085)

Fournisseur:  ProSci Inc.
Description:   ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI40-617)

Fournisseur:  ProSci Inc.
Description:   GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. Recombinant murine GM-CSF (40-617) is a 14.2 kDa globular protein consisting of 124 amino acids residues. Recombinant murine GM-CSF (40-621) is a 14.5 kDa globular protein consisting of 128 amino acids residues.
UOM:  1 * 20 µG
Numéro de catalogue: (PRSI30-296)

Fournisseur:  ProSci Inc.
Description:   UNCX is a transcription factor involved in somitogenesis and neurogenesis. It is required for the maintenance and differentiation of particular elements of the axial skeleton. It may act upstream of PAX9. UNCX plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI79-230)

Fournisseur:  ProSci Inc.
Description:   This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-κ-B in mature T lymphocytes. Required for interleukin-2 (IL2) production.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-732)

Fournisseur:  ProSci Inc.
Description:   Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.
UOM:  1 * 1 EA
Numéro de catalogue: (CAMA022.5292)

Fournisseur:  CAMAG
Description:   Glass lid for CAMAG® Twin trough chamber made from DURAN® Borosilicate 3.3 for 20×10 cm plates
UOM:  1 * 1 ST
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