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Ace+Method+Development+Kits
Numéro de catalogue:
(BOSSBS-3162R-HRP)
Fournisseur:
Bioss
Description:
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), EPHA2, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Recruits the ubiquitin ligase MDM2 to P53/TP53 in the nucleus, and thereby regulates P53/TP53 activity, P53/TP53 ubiquitination and proteasomal degradation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13682R-HRP)
Fournisseur:
Bioss
Description:
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1774R-HRP)
Fournisseur:
Bioss
Description:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1778R-FITC)
Fournisseur:
Bioss
Description:
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1825R-HRP)
Fournisseur:
Bioss
Description:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
UOM:
1 * 100 µl
Fournisseur:
Merck
Description:
Les solvants EMSURE® sont adaptés à un large éventail d'applications classiques de laboratoire et sont fréquemment utilisés pour des applications réglementées et hautement exigeantes. EMSURE® fournit les meilleures spécifications de produit dans le monde entier. Nous déclarons que notre gamme EMSURE® est conforme à l'ACS, avec la partie réactif de la Pharmacopée européenne (Reag. Ph. Eur.) et aussi avec les normes ISO.
Numéro de catalogue:
(BOSSBS-6710R-A488)
Fournisseur:
Bioss
Description:
NGL-1 is a single pass type I membrane protein that acts as a cell adhesion molecule. It contains nine leucine-rich repeats (LRR) and one Ig-like C2-type domain. NGL-1 is predominantly expressed in the striatum and the cerebral cortex of both the embryonic and adult brain. NGL-1 specifically interacts with Netrin G1 (a molecule involved in axon guidance in the developing central nervous system) via its LRR region. NGL-1 plays a role in the regulation of neurite outgrowth of developing thalamic neurons. Soluble NGL-1 inhibits thalamic axon outgrowth while NGL-1 that is bound to the surface of developing thalamocortical axons stimulates growth. NGL-1 also interacts with Whirlin possibly stablizing interstereociliar links.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6228R-A350)
Fournisseur:
Bioss
Description:
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6228R-A680)
Fournisseur:
Bioss
Description:
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
UOM:
1 * 100 µl
Numéro de catalogue:
(710-1967)
Fournisseur:
DOEHLER GROUP
Description:
PCR broth for fast and universal detection of beer spoiling microorganisms, such as lactobacilli, pediococci, Pectinatus and Megasphaera in yeast and clear/cloudy beer samples. NBB®-PCR (pH 5,7 ±0,2) is a ready-to-use enrichment broth for the detection of beer spoiling bacteria by PCR and real-time PCR methods. NBB®-PCR is compatible with all standard PCR and real-time PCR methods from different manufacturers. Due to an optimised and regulated quality-controlled production process, the medium does not contain any ingredients, which impair DNA amplification and detection (realtime PCR). In addition the medium is free from contaminating DNA, which is controlled and ensured by internal and external validations. The medium is optimized for microbiological enrichment and therefore allows no culture detection of bacteria, because no indicator dye is included.
NBB®-PCR broth can be used for the molecular biological detection of:.
UOM:
1 * 9 ST
Fournisseur:
Avantor
Description:
These ultra-inert Avantor® ACE® Excel® C8 columns provide great reproducibility and column lifetime. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.
Numéro de catalogue:
(BOSSBS-6245R)
Fournisseur:
Bioss
Description:
Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.
UOM:
1 * 100 µl
Fournisseur:
MACRON AVANTOR BRAND
Description:
Acide borique ≥99.5%, granuleux, AR® ACS, Macron Fine Chemicals™
Numéro de catalogue:
(BOSSBS-13201R-A680)
Fournisseur:
Bioss
Description:
The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13201R-A555)
Fournisseur:
Bioss
Description:
The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13201R-A488)
Fournisseur:
Bioss
Description:
The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.
UOM:
1 * 100 µl
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