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Fournisseur:  Thermo Scientific
Description:   Gel de silice, en grenailles ACS -6+18 Mesh dessiccant, avec indicateur
Fournisseur:  VWR Chemicals
Description:   Acide chromotropique sel disodique dihydraté ≥98.0% Reag. Ph. Eur., ACS pour analyses
UOM:  1 * 25 g
Fournisseur:  ENZO LIFE SCIENCES
Description:   Caspase-3 inhibitor
New Product
Fournisseur:  Avantor
Description:   Avantor® ACE® Glycan is a high performance stationary phase designed for the analysis of 2-aminobenzamide labelled glycans by hydrophilic interaction liquid chromatography (HILIC). These ultra-inert, high efficiency columns provide excellent column lifetime and reproducibility with buffers and mobile phases typically utilised for glycan analysis. Two particle sizes are available to enable both high resolution and rapid separations on HPLC and UHPLC instrumentation.
Fournisseur:  Thermo Scientific
Description:   Phénol 99+% stabilisé ACS
Fournisseur:  VWR Chemicals
Description:   Les étalons pour le point d'éclair PMCC (en coupelle fermée) sont testés et certifiés en conformité avec la norme ASTM D93 'Méthode pour la détermination du point d’éclair à l’aide de l’appareil Pensky-Martens en vase clos - Procédure A'.
Fournisseur:  Thermo Scientific
Description:   Sodium tétraphénylborate ≥99.5% ACS
Numéro de catalogue: (BOSSBS-9264R-A647)

Fournisseur:  Bioss
Description:   The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF215 (ring finger protein 215), is a 377 amino acid multi-pass membrane protein containing one RING-type zinc finger. The gene encoding RNF215 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8218R-A647)

Fournisseur:  Bioss
Description:   Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF∫ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The FAM59A gene product has been provisionally designated FAM59A pending further characterization.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
UOM:  1 * 100 µl
Fournisseur:  ENZO LIFE SCIENCES
Description:   Selective ligand for toll-like receptor 7 (TLR7) via IFN.
New Product
Numéro de catalogue: (BOSSBS-11489R-A680)

Fournisseur:  Bioss
Description:   TNRC6B is a 1723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukaemias.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0380R-CY5)

Fournisseur:  Bioss
Description:   Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11510R-A680)

Fournisseur:  Bioss
Description:   Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterised by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. BBS patients also have an increased risk of developing diabetes, hypertension, and congenital heart defects. BBS is a heterogeneous disorder mapping to eight genetic loci and encoding eight proteins, BBS1-BBS8. Five BBS proteins encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS2 contains two overlapping genes: BBS2L1 and BBS2L2. BBSL1 was re-named BBS7, whereas BBS2L2 independently functions as BBS1. BBS7 contains 672 amino acids and is expressed at low to moderate levels in most human tissues.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11830R-A647)

Fournisseur:  Bioss
Description:   Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA X also referred to as Carbonic anhydrase-related protein X (CA-RP X) or Cerebral protein 15, is a member of the carbonic anhydrase family that lacks two of the three Zn-binding motifs essential for carbonic anhydrase activity. For this reason, CA X does not exhibit catalytic activity. It is expressed primarily in brain and kidney and may play a role in brain development.
UOM:  1 * 100 µl
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