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Ace+Method+Development+Kits
Fournisseur:
LIEDER JOHANNES
Description:
The slides are arranged and compiled, so that each enlarges the subject line of the proceeding one.
Numéro de catalogue:
(PRSI27-776)
Fournisseur:
ProSci Inc.
Description:
SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-7824R-A555)
Fournisseur:
Bioss
Description:
The GINS complex is composed of four subunits, encoded by SLD5, PSF1, PSF2, and PSF3. In S. cerevisiae, it was first identified by genetic and biochemical methods to determine factors interacting with Sld5p. Genetic interactions between these four genes also suggest that they act together. The GINS complex was independently isolated in a large scale screen for cell cycle defects. A similar complex is found in Xenopus and has a ring-like structure. In yeast, all four genes are essential and cells defective in SLD5, PSF1, or PSF2 are impaired in their ability to replicate DNA. The complex localizes to origins of DNA replication and Sld5p was previously implicated as functioning in DNA replication due to its genetic interaction with DPB11. Additional genetic and biochemical interactions of the GINS complex with Dpb11p, Dpb2p, and Sld3p suggest that it functions in some way at the replication fork during DNA synthesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7824R-FITC)
Fournisseur:
Bioss
Description:
The GINS complex is composed of four subunits, encoded by SLD5, PSF1, PSF2, and PSF3. In S. cerevisiae, it was first identified by genetic and biochemical methods to determine factors interacting with Sld5p. Genetic interactions between these four genes also suggest that they act together. The GINS complex was independently isolated in a large scale screen for cell cycle defects. A similar complex is found in Xenopus and has a ring-like structure. In yeast, all four genes are essential and cells defective in SLD5, PSF1, or PSF2 are impaired in their ability to replicate DNA. The complex localizes to origins of DNA replication and Sld5p was previously implicated as functioning in DNA replication due to its genetic interaction with DPB11. Additional genetic and biochemical interactions of the GINS complex with Dpb11p, Dpb2p, and Sld3p suggest that it functions in some way at the replication fork during DNA synthesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(8196-02)
Fournisseur:
Avantor
Description:
Ces colonnes ont recours aux résines polymères BAKERBOND® DVB issues de la technologie de microparticules polymériques ultra-clean. Ces particules de résine affichent une large surface, elles sont hautement rigides, stables sur une plage de pH allant de 1 à 14, mouillables à l’eau et non impactées par le séchage par absorbant. On recommande de recourir à ces colonnes lorsqu'on utilise des méthodes de détection avancées.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-8381R-A680)
Fournisseur:
Bioss
Description:
Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localised to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB50629)
Fournisseur:
AAT BIOQUEST INC
Description:
Norfentanyl-BSA Conjugate is an excellent probe to develop antibodies, assays and tests for detecting norfentanyl substances.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI28-200)
Fournisseur:
ProSci Inc.
Description:
ZNF22 encodes a protein that is expressed in the epithelial component of the developing tooth organ during early bud and cap stages as well as in osteoblasts of craniofacial bone and the developing tongue.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-192)
Fournisseur:
ProSci Inc.
Description:
TBX20 is a member of the T-box transcription factor family expressed in the developing heart, eye, ventral neural tube, and limbs, indicating a possible role in regulating development of these tissues.
UOM:
1 * 50 µG
Fournisseur:
Binhold, Paul Lehrmittel
Description:
See the complete stages of development. Study the normal position of child before birth with this model plus the human reproductive and urinary systems.
Numéro de catalogue:
(PRSI28-704)
Fournisseur:
ProSci Inc.
Description:
Homeobox proteins are transcription factors notable for their ability to regulate embryogenesis. The reproductive homeobox proteins (Rhox) are expressed in a cell type-specific manner; several are hormonally regulated, and their expression pattern during postnatal testis development corresponds to their chromosomal position. Most of the Rhox proteins are expressed in Sertoli cells, the nurse cells in direct contact with developing male germ cells, suggesting that they regulate the expression of somatic-cell gene products critical for germ cell development.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-594)
Fournisseur:
ProSci Inc.
Description:
GPCR5A is a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. Its gene may play a role in embryonic development and epithelial cell differentiation.This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-3092R-A680)
Fournisseur:
Bioss
Description:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB50627)
Fournisseur:
AAT BIOQUEST INC
Description:
Norfentanyl-Biotin is an excellent probe for developing assays and tests for detecting norfentanyl substances.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI27-805)
Fournisseur:
ProSci Inc.
Description:
ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue.
UOM:
1 * 50 µG
Numéro de catalogue:
(AATB344)
Fournisseur:
AAT BIOQUEST INC
Description:
5(6)-Carboxyrhodamine 6G ethylenediamine is a building block for developing rhodamine bioconjugates.
UOM:
1 * 1 mg
New Product
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