Ace+Method+Development+Kits
Numéro de catalogue:
(AATB21244)
Fournisseur:
AAT BIOQUEST INC
Description:
5-(and-6)-Carboxy SNARF-1 alkyne is an excellent azido-reactive building block that can be used for developing SNARF-1 pH probes via the well-known click chemistry.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB21172)
Fournisseur:
AAT BIOQUEST INC
Description:
5-(and-6)-Carboxy SNARF-4F Maleimide is an excellent thiol-reactive building block that can be readily used for developing SNARF-4F pH probes.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB21247)
Fournisseur:
AAT BIOQUEST INC
Description:
5-(and-6)-Carboxy SNARF-5F Maleimide is an excellent thiol-reactive building block that can be readily used for developing SNARF-5F pH probes.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(BOSSBS-3717R-CY5.5)
Fournisseur:
Bioss
Description:
P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3717R-A680)
Fournisseur:
Bioss
Description:
P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localised guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localised in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3717R-A750)
Fournisseur:
Bioss
Description:
P73 protein is a structural and functional homologue of p53, a tumor suppressor gene. In this study, The p73 protein, p19ras, by the yeast two-hybrid screening method. Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, Ras proteins are known to be small membrane-localised guanine nucleotide-binding proteins. However, unlike other Ras proteins, p19ras is localised in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus. Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity. In this study, when p19ras was bound to MDM2, it further inhibited the association of MDM2 to the p73 protein. Therefore, this study presents a novel pathway of Ras signaling that occurs in the nucleus, involving p19ras and p73.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI5881)
Fournisseur:
ProSci Inc.
Description:
TRIM71 Antibody: TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development, and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.
UOM:
1 * 1 EA
Numéro de catalogue:
(AATB1079)
Fournisseur:
AAT BIOQUEST INC
Description:
iFluor® dyes are developed for labeling proteins, in particular, antibodies.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB72704)
Fournisseur:
AAT BIOQUEST INC
Description:
FastClick™ Cy7 Azide contains both the CAG moiety of FastClick (for assisting click efficiency) and Cy7 fluorophore (as the fluorescence tag) for developing Cy7-based fluorescent probes.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB72714)
Fournisseur:
AAT BIOQUEST INC
Description:
FastClick™ 6-ROX Azide contains both the CAG moiety of FastClick (for assisting click efficiency) and 6-ROX fluorophore (as the fluorescence tag) for developing 6-ROX-based fluorescent probes.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB50015)
Fournisseur:
AAT BIOQUEST INC
Description:
3-Amino-5-morpholinomethyl-2-oxazolidinone (AMOZ)-HRP conjugate is used for developing an ELISA assay for quantifying 3-Amino-5-morpholinomethyl-2-oxazolidinone (AMOZ).
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(BOSSBS-1531R-A680)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1531R-A488)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB359)
Fournisseur:
AAT BIOQUEST INC
Description:
6-TAMRA ethylenediamine is a building block for developing TAMRA bioconjugates.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI25-038)
Fournisseur:
ProSci Inc.
Description:
MNX1 contains 1 homeobox DNA-binding domain. MNX1 is a putative transcription factor involved in pancreas development and function. Defects in MNX1 are a cause of Currarino syndrome.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-221)
Fournisseur:
ProSci Inc.
Description:
Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.
UOM:
1 * 50 µG
Appel de prix
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