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Chem-Durance®+Bio+Precision+Pump+Tubing
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Chem-Durance®+Bio+Precision+Pump+Tubing
Numéro de catalogue:
(BOSSBS-7048R-CY3)
Fournisseur:
Bioss
Description:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM:
1 * 100 µl
Fournisseur:
BOCHEM
Description:
Precision forceps made from PTFE coated stainless steel.
Numéro de catalogue:
(FSCI91117-10)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Pinces de précision, Acier inoxydable, Curved, Pointes: Fine, 100 mm
UOM:
1 * 1 ST
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(FSCI91115-10)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Pinces de précision, Acier inoxydable, Straight, Pointes: Fine, 110 mm
UOM:
1 * 1 ST
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
VWR Collection
Description:
Support d'agitation pour 10 tubes de 10/15 ml et 16 tubes de 5/7 ml
Numéro de catalogue:
(LOVI214100)
Fournisseur:
Lovibond
Description:
MD 600 photometer is for precise and accurate measurements with a small footprint.
UOM:
1 * 1 ST
Fournisseur:
Brand
Description:
À volume variable.
Numéro de catalogue:
(FSCI11254-20)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Pinces de précision, Auteur: Dumont, Inox, Straight, Pointes: Fine, 110 mm
UOM:
1 * 1 ST
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
Saint Gobain Life Sciences
Description:
Sani-Tech® ultra-pure platinum-cured silicone tubing meets the stringent requirements of the biopharmaceutical market.
Numéro de catalogue:
(PRSI25-956)
Fournisseur:
ProSci Inc.
Description:
ATP2B4 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B4 is the plasma membrane calcium ATPase isoform 4.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.
UOM:
1 * 50 µG
Numéro de catalogue:
(233-0223)
Fournisseur:
OUTILS RUBIS SA
Description:
High precision micro scissors with extra-fine tips.
UOM:
1 * 1 ST
Fournisseur:
Freudenberg Medical Europe GmbH
Description:
PharmaFocus® Premium Reinforced Silicone Tubing is available with single-braid reinforcement for enhanced performance in high pressure and vacuum applications. All reinforced silicone tubing is manufactured with an inner layer of platinum-cured silicone for ultra-pure fluid transfer and meets a diverse range of pharmaceutical and bioprocessing applications.
Fournisseur:
SP Industries
Description:
Susceptibility matched tubes can reduce the sample volume down to 1/3 by minimising the susceptibility gradients occurring at the solvent-air interface.
Fournisseur:
Thermo Fisher Scientific
Description:
Tubes PP/Rack PC/PP. Low profile 5,0 ml externally-threaded universal tubes provide a robust solution for solid or liquid sample storage. Available in configurations that meet your tracking and packaging requirements, the low profile universal tube features 2D barcodes, graduations, a white patch for labelling, and a wide mouth design for easy addition and extraction of sample material. Its externally-threaded design minimises contamination risk in manual handling procedures. The tubes and rack are rated for storage down to vapor phase liquid nitrogen temperatures.
Fournisseur:
Simport Scientific
Description:
Economical, optically clear dishes are precision-molded from biomedical-grade PS, making cultures visible without distortion.
Fournisseur:
Avantor Fluid Handling
Description:
Get leak-free connection to barbed fittings.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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