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Numéro de catalogue: (BOSSBS-15385R-CY7)

Fournisseur:  Bioss
Description:   Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalised into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6694R-A680)

Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
UOM:  1 * 100 µl
Fournisseur:  THERMO MATRIX TECHNOLOGIES
Description:   En PP vierge de qualité médicale, classe VI. Portoirs permettant le stockage des échantillons dans pratiquement n'importe quelle condition de laboratoire (température ambiante comme azote liquide en phase gazeuse). Un code-barres 2D unique et permanent, gravé au laser, est apposé à la base de chaque tube, pour une identification et un suivi exacts des échantillons.
Environmentally Preferable
Numéro de catalogue: (AATBCCT100)

Fournisseur:  AAT BIOQUEST INC
Description:   Les tubes d'échantillonnage CytoCite™ sont des tubes en polypropylène à paroi mince de 500 μl validés pour une utilisation avec le fluoromètre Cytocite ou Qubit.
UOM:  1 * 500 ST
New Product
Fournisseur:  Spectrum Laboratories
Description:   Ready-to-use laboratory dialysis systems featuring proprietary Ultra-pure Biotech Cellulose Ester (CE) Membrane. Biotech Grade CE is a low protein-binding synthetic membrane available in 9 precise MWCO's with no heavy metal and sulfide contaminants. The cylindrical tubing geometry prevents sample dilution (associated with cassette-type devices) and provides open access for total volume retrieval by pipette. Only the Float-A-Lyzer® G2 assures a 95 to 98% sample recovery while maintaining 99% sample purity and <1% sample dilution. The leakproof screw-on cap with sealing o-ring provides easy access with included pipette for loading, in-process testing and sample retrieval, without the risk of needle punctures. The included floatation ring improves sample buoyancy and vertical orientation during dialysis. The sleek design allows multiple samples to be dialysed in the same reservoir.
Numéro de catalogue: (MILFEZSTREAM)

Fournisseur:  Merck
Description:   Simply connect the pump to your manifold or filtration apparatus and place the discard tubing to drain and you are ready to filter. There is no need to use additional containers to capture the waste liquid. This brings a significant time saving versus traditional vacuum/pressure pumps or in-house vacuum because the following steps are eliminated: disconnecting the waste containers, emptying liquid waste, cleaning/decontaminating, re-installing the waste containers.
UOM:  1 * 1 ST
Numéro de catalogue: (BOSSBS-7921R)

Fournisseur:  Bioss
Description:   Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.Involvement in disease:Defects in ROBO2 are the cause of vesicoureteral reflux type 2 (VUR2) . VUR is a complex, genetically heterogeneous developmental disorder characterized by the retrograde flow of urine from the bladder into the ureter and is associated with reflux nephropathy, the cause of 15% of end-stage renal disease in children and young adults.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11518R-A680)

Fournisseur:  Bioss
Description:   This gene belongs to the forkhead family of transcription factors which is characterised by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7002R-A680)

Fournisseur:  Bioss
Description:   PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7002R-CY3)

Fournisseur:  Bioss
Description:   PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7002R-CY5.5)

Fournisseur:  Bioss
Description:   PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7002R-CY7)

Fournisseur:  Bioss
Description:   PAGE4 belongs to the GAGE family of genes which are expressed in a variety of tumors and in some fetal and reproductive tissues. PAGE4 is strongly expressed in prostate and prostate cancer, but is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).
UOM:  1 * 100 µl
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