Masterflex+Single-use+Flow+Sensor
Numéro de catalogue:
(BOSSBS-2158R-CY5.5)
Fournisseur:
Bioss
Description:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5899R-A680)
Fournisseur:
Bioss
Description:
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5175R-CY3)
Fournisseur:
Bioss
Description:
Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2158R-A680)
Fournisseur:
Bioss
Description:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2158R-A555)
Fournisseur:
Bioss
Description:
Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040). PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(ROCK600-609-209)
Fournisseur:
Rockland Immunochemicals
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency.
UOM:
1 * 1 mg
Numéro de catalogue:
(NOVUNB100-56566)
Fournisseur:
Novus Biologicals
Description:
The TLR4 Antibody (76B357.1) from Novus Biologicals is a mouse monoclonal antibody to TLR4. This antibody reacts with human, mouse, rat. The TLR4 Antibody (76B357.1) has been validated for the following applications: Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, In vitro assay, Flow (Cell Surface), Flow (Intracellular), CyTOF-ready.
UOM:
1 * 0,1 mg
Fournisseur:
SGE a Trajan company
Description:
The o-ring prevents gas leaks and maintains a uniform flow path through the inlet, where even small leaks can cause sample loss - affecting accuracy and reproducibility of results.
Numéro de catalogue:
(GENO786-1992)
Fournisseur:
G-Biosciences
Description:
T4 recombination mediator protein, UvsY plays important roles in homologous recombination (HR). During HR, the UvsX recombinase competes with the prebound single-stranded binding protein gp32 for DNA-binding sites and UvsY stimulates this filament nucleation event.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BOSSBS-4757R-HRP)
Fournisseur:
Bioss
Description:
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.
UOM:
1 * 100 µl
Numéro de catalogue:
(ROCK600-100-098)
Fournisseur:
Rockland Immunochemicals
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency.
UOM:
1 * 1 mg
Numéro de catalogue:
(ROCK600-109-098)
Fournisseur:
Rockland Immunochemicals
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency.
UOM:
1 * 1 mg
Numéro de catalogue:
(ROCK700-100-096)
Fournisseur:
Rockland Immunochemicals
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency.
UOM:
1 * 1 mg
Numéro de catalogue:
(BOSSBS-5899R-A647)
Fournisseur:
Bioss
Description:
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(NOVUNBP1-28904B)
Fournisseur:
Novus Biologicals
Description:
Rabbit Polyclonal GPR49/LGR5 Antibody [Biotin]. Tested Applications: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin. Tested Reactivity: Human.
UOM:
1 * 0,1 mL
Numéro de catalogue:
(BOSSBS-0634R-A350)
Fournisseur:
Bioss
Description:
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
UOM:
1 * 100 µl
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