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PharMed®+BPT+Precision+Pump+Tubing
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PharMed®+BPT+Precision+Pump+Tubing
Fournisseur:
EDWARDS HIGH VACUUM METTLER
Description:
ATEX RV pumps have an external ATEX classification of Ex II 2G IIC T4 or Ex II 2G IIB T4 and internal ATEX classification Ex II 3G c IIB T4. They are suitable for use in potentially explosive atmospheres such as hazardous area pumping. They are supplied with the gas ballast port which must be fitted with an inert gas purge while pumping flammable gasses or vapours to dilute such gases or vapours below the lower explosive limit.
Fournisseur:
Welch by Gardner Denver
Description:
Silicone oil, 0,5 l, XT 704
Numéro de catalogue:
(VACU25741750)
Fournisseur:
VACUUBRAND GMBH + CO
Description:
Chemistry diaphragm pumps from VACUUBRAND for aggressive gases and vapors are available in the basic version, with two-point or VARIO® control. Their construction with fluoropolymers makes them very resistant to chemical vapors from inlet to exhaust.
UOM:
1 * 1 ST
Numéro de catalogue:
(ENZOALX801035C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Bile Salts
Bile salts are important physiological agents that serve a number of functions, including absorption, solubilization, transport and secretion of lipids. In the liver, they participate in the generation of bile flow and the secretion of cholesterol and phospholipids, such as phosphatidylcholine. When released into the intestine, they facilitate the uptake of cholesterol, fat-soluble vitamins and other lipids. Moreover, the biosynthesis of bile acids from cholesterol is the most significant pathway for the elimination of cholesterol from the body. However, because of their detergent properties, bile acids are inherently cytotoxic and disruptions in their normal transport or secretion can result in a variety of pathophysiological conditions. BSEP Bile formation is an important function of the liver. It is mediated by hepatocytes which generate bile flow within the bile canaliculi by continuous vectorial secretion of bile salts and other solutes across their canalicular (apical) membrane. Bile secretion is mediated by several ATP-binding cassette (ABC) transporters located in the canalicular membrane of hepatocytes. Among these ABC transporters, the bile salt export pump (BSEP or ABCB11) represents the primary, if not sole transport system for the canalicular excretion of bile salts. Bile secretory failure results in cholestasis and progressive familial intrahepatic cholestasis (PFIC) in infancy represents a group of inherited cholestatic diseases that are classified into three subtypes. One of these subtypes, PFIC II, is associated with mutations in the BSEP gene. PFIC patients with mutations in the BSEP gene have normal γ-glutamyltransferase activity, low concentrations of bile salts in bile, and an absence of bile duct proliferation. Additionally, human obesity is associated with altered cholesterol homeostasis including increased production and turnover, as well as secretion of excess cholesterol from the liver into bile. BSEP is a multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-ancoring domain and an ATP-binding cassette (ABC) domain. The membrane-anchoring domain is composed of six helixes buried in the lipid bilayer of the plasma membrane and the ATP binding ABCs are exposed to the cytosol. The membrane-anchoring domain helixes are thought to form channels spanning the plasma membrane.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BOSSBS-5504R-A647)
Fournisseur:
Bioss
Description:
Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53. Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, enabling expression of miR-34b and miR-34c, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent MYC translation. Acts as a negative regulator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB. Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4: the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4). Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stimulation, inducing F-actin rearrangement.
UOM:
1 * 100 µl
Fournisseur:
Sampling Systems
Description:
Perfect for sampling low viscosity liquids.
Numéro de catalogue:
(NEWPPMPL117)
Fournisseur:
NEW PIG
Description:
Suitable for aggressive chemicals, solvents, de-greasers and more.
UOM:
1 * 1 ST
Numéro de catalogue:
(612-2080)
Fournisseur:
DELTALAB
Description:
Pipette pump support rack made of acrylic resin and designed to keep in position four pipette pumps.
UOM:
1 * 1 ST
Numéro de catalogue:
(VACU20797150)
Fournisseur:
VACUUBRAND GMBH + CO
Description:
Rotary vane pumps from VACUUBRAND offer great performance in a compact design. Even with the gas ballast open, they enable a very good ultimate vacuum. You also benefit from extended oil change and maintenance intervals thanks to optimised lubrication circuit and large usable oil volume.
UOM:
1 * 1 ST
Numéro de catalogue:
(224-0000)
Fournisseur:
NRG DEVELOPMENTS LTD
Description:
Drum pump, Adaptateur 2" Mauser pour conteneurs de 205 l
UOM:
1 * 1 ST
Numéro de catalogue:
(BARND8964)
Fournisseur:
Thermo Fisher Scientific
Description:
Low water level pump protector, Pour: Water purification system, Nanopure®
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-5504R-CY5.5)
Fournisseur:
Bioss
Description:
Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53. Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3: phosphorylation of FOXO3 leads to promote nuclear localization of FOXO3, enabling expression of miR-34b and miR-34c, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent MYC translation. Acts as a negative regulator of mTORC1 signaling by mediating phosphorylation and inhibition of RHEB. Part of the atypical MAPK signaling via its interaction with ERK3/MAPK6 or ERK4/MAPK4: the precise role of the complex formed with ERK3/MAPK6 or ERK4/MAPK4 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPK (ERK3/MAPK6 or ERK4/MAPK4), ERK3/MAPK6 (or ERK4/MAPK4) is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6 (or ERK4/MAPK4). Mediates phosphorylation of HSP27/HSPB1 in response to PKA/PRKACA stimulation, inducing F-actin rearrangement.
UOM:
1 * 100 µl
Fournisseur:
BUCHI
Description:
Le KjelFlex K-360 automatisé est disponible dans plusieurs configurations en fonction de l'application et de la capacité de traitement. En règle générale, il s'agit d'une combinaison de l'unité principale et des options modulaires de la pompe protégée contre les acides, du titrage ou du type de protection contre les éclaboussures. La participation des opérateurs au processus a été considérablement réduite.
Fournisseur:
VACUUBRAND
Description:
Vacuum aspiration system accessory, Quick coupling, PVDF, to connect a collection bottle to a pump unit BVC or to a BVC basic, good chemical resistance, autoclavable
Fournisseur:
VITLAB
Description:
Flacons en PP blanc ou translucide.
Fournisseur:
VWR Collection
Description:
Ces tubes à centrifuger étanches sont idéaux pour les applications environnementales, comme l’analyse de l’eau et autres applications où les tubes sont susceptibles de contaminer les échantillons.
Appel de prix
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 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
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Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
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