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PharmaPure®+Precision+Pump+Tubing
Numéro de catalogue:
(BOSSBS-0423R-A350)
Fournisseur:
Bioss
Description:
Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50% of gliomas.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1437R-A647)
Fournisseur:
Bioss
Description:
MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
UOM:
1 * 100 µl
Fournisseur:
BURKLE
Description:
Cuvettes pour de nombreuses applications. En laboratoire, cabinet médical, hôpital, pharmacie, dans le domaine alimentaire – partout où des instruments, des appareils, des biens et des pièces de précision doivent être stockées dans un endroit propre.
Numéro de catalogue:
(BOSSBS-2200R-A680)
Fournisseur:
Bioss
Description:
LDL and HDL transport both dietary and endogenous cholesterol in the plasma. LDL is the main transporter of cholesterol and cholesteryl esters and makes up more than half of the total lipoprotein in plasma. LDL is absorbed by the liver and other tissues via receptor mediated endocytosis. The cytoplasmic domain of the LDL receptor facilitates the formation of coated pits; receptor-rich regions of the membrane. The ligand binding domain of the receptor Recognises apo-B100 on LDL, resulting in the formation of a clathrin-coated vesicle. ATP-dependent proton pumps lower the pH inside the vesicle resulting dissociation of LDL from its receptor. After loss of the clathrin coat the vesicles fuse with lysozomes, resulting in peptide and cholesteryl ester enzymatic hydrolysis. The LDL receptor can be recycled to the cell membrane. Insulin, tri-iodothyronine and dexamethasome have shown to be involved with the regulation of LDL receptor mediated uptake. The protein component of LDL is apolipoprotein B100. LDL contains 2022% protein, 1015% triglycerides, 2028% phospholipids, 3748% cholesteryl esters and 810% cholesterol.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12549R-A680)
Fournisseur:
Bioss
Description:
Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (AH) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function. The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts. The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21.
UOM:
1 * 100 µl
Fournisseur:
OUTILS RUBIS SA
Description:
Cobalt-chromium-molybdenum alloy. These forceps with very high Vicker hardness offer a range of physical, chemical and technological properties that make them appropriate for a wide variety of applications. Exceptional good tolerance on human tissues.
Numéro de catalogue:
(BOSSBS-12956R)
Fournisseur:
Bioss
Description:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4559R-CY7)
Fournisseur:
Bioss
Description:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8166R-CY7)
Fournisseur:
Bioss
Description:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(TEXWCM502)
Fournisseur:
Texwipe
Description:
Coventry™ microtips are designed for precision applications needing pinpoint accuracy. The tapered porous polyvinylidene fluoride tip is effective as a stylus or pick for areas with tight tolerances.
UOM:
1 * 1.200 ST
Fournisseur:
Texwipe
Description:
Ces écouvillons stériles sont fabriqués à 100% en coton de qualité USP. Ils sont fixés sur une tige à l'aide d'une colle aqueuse. Les écouvillons sont fabriqués conformément à des tolérances strictes et uniformes, grâce à des processus automatisés haute précision.
Fournisseur:
VWR Collection
Description:
Les pipettes ergonomiques hautes performances (Ergonomic High Performance, EHP) de VWR® sont exactes et précises. Les nouvelles fonctionnalités ergonomiques garantissent un pipetage confortable même en cas d'utilisation prolongée.
Numéro de catalogue:
(KIMB61930)
Fournisseur:
KIMBERLY CLARK
Description:
KIMTECH PREP® SCOTTPURE™ Wipers are designed for wiping tasks where precision and reliability are essential.
UOM:
1 * 6 ROU
Fournisseur:
SI Analytics
Description:
Le Titronic® 300 est une burette à moteur pour le titrage manuel et un instrument de dosage précis pour les liquides superflus, les solvants et les agents de titrage. Il peut être utilisé comme un instrument autonome mais peut également fonctionner comme une burette de titrage et de dosage dans les systèmes de titrage contrôlés par ordinateur (automatiques). Idéal pour les laboratoires dans lesquels une grande précision et une flexibilité sont requises.
Numéro de catalogue:
(BOSSBS-1698R-CY5.5)
Fournisseur:
Bioss
Description:
Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.
UOM:
1 * 100 µl
Fournisseur:
KIMBERLY CLARK
Description:
Ces lingettes haute qualité 100% pure fibre sont conçues pour l'essuyage de précision telles que le nettoyage de verrerie, d'équipements et de surfaces délicates. Elles sont également adaptées au nettoyage des liquides et des poussières et dotées d'éléments anti-statiques qui réduisent le peluchage et les décharges anti-statiques.
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 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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