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Single-use+Pressure+Sensor
Numéro de catalogue:
(BOSSBS-9491R)
Fournisseur:
Bioss
Description:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9491R-CY5)
Fournisseur:
Bioss
Description:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9491R-A647)
Fournisseur:
Bioss
Description:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9491R-HRP)
Fournisseur:
Bioss
Description:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Fournisseur:
Restek
Description:
These single stage stainless steel VOC regulators features stainless steel diaphragm, two pressure gauges, CGA-180 fitting and Kel-F® seat.
Numéro de catalogue:
(BOSSBS-9491R-A555)
Fournisseur:
Bioss
Description:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(461-0324)
Fournisseur:
JULABO GmbH
Description:
Le générateur de froid à refroidissement air/eau AWC100 est conçu pour éliminer de faibles quantités de chaleur dans des systèmes externes où la température de refroidissement est supérieure à la température ambiante et où il n'est pas nécessaire de contrôler la température. Le générateur de froid qui ne dispose pas d'une unité de réfrigération est particulièrement adapté à une utilisation dans des circuits avec élément Peltier, appareils analytiques, polarimètres, réfractomètres et caméras CCD. La vitesse du ventilateur (c'est-à-dire la capacité de refroidissement) peut être ajustée en deux paliers, la capacité de refroidissement dépendant de la différence de température entre le retour et la température ambiante. Principe de refroidissement: le liquide de bain chaud est pompé via l'échangeur thermique. L'échangeur thermique est refroidi par un moteur de ventilation et élimine donc la chaleur produite.
UOM:
1 * 1 ST
Fournisseur:
Agilent
Description:
Stainless steel capillaries are made of flexible stainless steel (0,6 mm OD) with ¹/₁₆" OD tubing at both ends to accept standard fittings.
Numéro de catalogue:
(GRSG600407)
Fournisseur:
Greisinger
Description:
This handheld meter with integrated absolute pressure sensor is suitable for measurements in air and non corrosive and non ionizing gases and liquids.
UOM:
1 * 1 ST
Fournisseur:
Merck
Description:
Pentafluorophenylhydrazine may be used as a derivatizing agent in the determination of semi-volatile carbonyl compounds in air and human plasma samples, using high-resolution gas chromatography coupled with gas chromatography (HRGC-MS) and liquid chromatography atmospheric-pressure chemical-ionization mass spectrometry (LC-APCI-MS-MS), respectively.
Fournisseur:
Avantor
Description:
These solvent inlet filters are used at the low pressure inlet side of the pump to help protect check valves, injector and column from particulate contamination from the eluent.
Fournisseur:
Rmoni
Description:
Rmoni offers complete end-2-end sensor solutions to set up an Environmental Monitoring Solutions (EMS) in hospitals, laboratories, pharmacies and cleanrooms. Keeping track of all critical parameters including temperature, humidity and many more. Ensuring product and process integrity during storage, handling and as well as transportation.
Numéro de catalogue:
(GILI37012000)
Fournisseur:
GILSON LCMS
Description:
The ASPEC® Positive pressure manifold uses positive pressure to improve reproducibility and recovery for solid phase extraction (SPE) applications.
UOM:
1 * 1 ST
Fournisseur:
HORIBA
Description:
Ces appareils de mesure étanches permettent de mesurer et d'afficher jusqu'à 11 paramètres simultanément avec une seule sonde. Grâce à leur conception robuste et leurs capteurs remplaçables sur site, ils sont idéaux pour une utilisation extérieure, par exemple lors du test des eaux souterraines ou de surface. Leur format compact et la dragonne permettent une utilisation d'une seule main.
Fournisseur:
Restek
Description:
These stainless steel regulators are the standard for ultra high purity and corrosion resistant pressure regulation. They are more easily purged of atmospheric components compared to brass gas regulators.
Numéro de catalogue:
(BOSSBS-6634R-A750)
Fournisseur:
Bioss
Description:
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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