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Single-use+Temperature+Sensor
Numéro de catalogue:
(BOSSBS-7719R-A647)
Fournisseur:
Bioss
Description:
DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.
UOM:
1 * 100 µl
Fournisseur:
SGE a Trajan company
Description:
Seringues pour passeurs pour PerkinElmer AutoSystem.
Numéro de catalogue:
(613-1609)
Fournisseur:
VWR Collection
Description:
Starter Kit incl. 4 UHP pipettes (0,5 - 10, 2 - 20, 20 - 200, 100 - 1000 µl), 4-position stand (613-1589) and 3 racks of tips.
UOM:
1 * 1 KIT
Numéro de catalogue:
(BOSSBS-4757R-A680)
Fournisseur:
Bioss
Description:
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidised rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.
UOM:
1 * 100 µl
Fournisseur:
SCHOTT AG Lighting and imaging
Description:
The EasyLED product line integrates advanced LED illumination with control functions in a single compact device. It is the ideal standard illumination system for routine inspections and education.
Numéro de catalogue:
(BOSSBS-1545R-A555)
Fournisseur:
Bioss
Description:
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodelling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
UOM:
1 * 100 µl
Fournisseur:
FLUOTICS
Description:
Fluotics manufactures a complete selection of automation tips compatible with Tecan fluent and Evo workstations. These automation tips are directly interchangeable with their Tecan automation tip counterpart, with no change to the labware definitions required.
Numéro de catalogue:
(BOSSBS-4757R-HRP)
Fournisseur:
Bioss
Description:
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9546R-CY7)
Fournisseur:
Bioss
Description:
FIBCD1 is a 461 amino acid single-pass membrane protein that contains one fibrinogen C-terminal domain and exists as multiple alternatively spliced isoforms. The gene encoding FIBCD1 maps to human chromosome 9, which contains 145 million base pairs, comprises 4% of the human genome and encodes nearly 900 genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6737R-A555)
Fournisseur:
Bioss
Description:
SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6737R-A350)
Fournisseur:
Bioss
Description:
SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0787R-CY5.5)
Fournisseur:
Bioss
Description:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7855R-A488)
Fournisseur:
Bioss
Description:
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2279R-A680)
Fournisseur:
Bioss
Description:
This gene encodes a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8480R-A750)
Fournisseur:
Bioss
Description:
RBMX2 is a 322 amino acid member of the IST3 family that contains one RRM (RNA recognition motif) domain. The RBMX2 gene is intronless, conserved in chimpanzee, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice and P.falciparum, and maps to human chromosome Xq25. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions that affect males more frequently as males carry a single X chromosome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9233R-CY5)
Fournisseur:
Bioss
Description:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF180 (ring finger protein 180), also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger. Expressed as three alternatively spliced isoforms, RNF180 is well conserved among vertebrates. RNF180 is expressed in brain, kidney, testis and uterus and localizes to the endoplasmic reticulum. RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway. RNF180 is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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