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Single-use+Temperature+Sensor
Numéro de catalogue:
(HACHLPV4439911002)
Fournisseur:
Hach
Description:
One portable instrument - all the key parameters.
UOM:
1 * 1 ST
New Product
Numéro de catalogue:
(215-4281)
Fournisseur:
DWK Life Sciences
Description:
Replacement GL 45 PTFE coated high-temperature silicone cap liner for the aluminium cap.
UOM:
1 * 10 ST
Numéro de catalogue:
(BOSSBS-6217R-CY7)
Fournisseur:
Bioss
Description:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6217R-CY5.5)
Fournisseur:
Bioss
Description:
Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. Considered to have intrinsic transcriptional activity, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), enhancing or repressing the transcriptional activity, respectively. Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, depending on the tissue, time and promoter contexts. Regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, CRY1 and NR1D1 itself, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, leading to the circadian pattern of clock genes expression. Therefore influences the period length and stability of the clock. Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, including PLIN2 and AVPR1A. Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, such as MMP3. Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. In liver, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, steroids and xenobiotics, such as SULT1E1.
UOM:
1 * 100 µl
Fournisseur:
VWR Collection
Description:
Électrodes de pH avec câble de 1 m fixé ou connecteur S7.
Fournisseur:
Binder
Description:
Temperature calibration certificate includes 9 measuring points at specified temperature, Pour: CB 60, CB 160, CB 220
Numéro de catalogue:
(111-2165)
Fournisseur:
Dräger
Description:
Carrying bag for two PARAT® C Single- or Traveller-Packs, Parat®, Pour: Parat® C
UOM:
1 * 1 ST
Fournisseur:
LGC Standards PROMOCHEM
Description:
ASTM 7 colour standard, single solution
Numéro de catalogue:
(620-0892)
Fournisseur:
VWR Collection
Description:
Ce thermomètre a été conçu pour indiquer les plages de températures critiques. La plage 4 à 6 °C est identifiée par des flèches.
UOM:
1 * 1 ST
Fournisseur:
Thermo Scientific
Description:
Usable temperature range: 25 to 250 °C (open system) and 25 to 315 °C (closed system)
Numéro de catalogue:
(AATB331)
Fournisseur:
AAT BIOQUEST INC
Description:
5-CR6G is the purified single isomer of 5(6)-CR6G.
UOM:
1 * 10 mg
New Product
Fournisseur:
WTW
Description:
Câble, AS/IDS-3, câble de connexion pour capteurs IDS avec raccord de connexion étanche, longueur 3 m, Longueur: 3 m
Numéro de catalogue:
(BOSSBS-3027R-CY5.5)
Fournisseur:
Bioss
Description:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
UOM:
1 * 100 µl
Fournisseur:
WTW
Description:
A 925-P, armure de protection d'un capteur IDS en présence d'une protection (A 925/K ou A 925/S)
Fournisseur:
HICHROM GAS CHROMATOGRAPHY
Description:
Application specifc columns for volatile organic compounds (VOCs), solvents and purgeable compounds. Due to the high max. temperature, they are ideal for two-parallel columns confg. in the same oven. A good alternative to the HI-624 giving different selectivity. It is a more robust than the HI-624 and can operate at higher temperatures.
Numéro de catalogue:
(BOSSBS-11277R-A750)
Fournisseur:
Bioss
Description:
DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen Signalling.
UOM:
1 * 100 µl
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