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Fournisseur:  Biotium
Description:   IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.

Fournisseur:  Bioss
Description:   E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of PCNP. May participate in methylation-dependent transcriptional regulation. Important for G1/S transition. Overexpression causes G1 phase cell arrest.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6389R-A647)

Fournisseur:  Bioss
Description:   E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of PCNP. May participate in methylation-dependent transcriptional regulation. Important for G1/S transition. Overexpression causes G1 phase cell arrest.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12242R-A350)

Fournisseur:  Bioss
Description:   Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-9317R-A350)

Fournisseur:  Bioss
Description:   Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4270R-A680)

Fournisseur:  Bioss
Description:   p18 INK4C is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4094R-A680)

Fournisseur:  Bioss
Description:   Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4094R-A750)

Fournisseur:  Bioss
Description:   Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6657R-A555)

Fournisseur:  Bioss
Description:   Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5244R-CY7)

Fournisseur:  Bioss
Description:   Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5244R-CY5)

Fournisseur:  Bioss
Description:   Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Protamines are cross-linked by interchain disulfide bonds around the DNA-helix. Protamines are localised in the nucleus. This protein is found only in the testis and belongs to the protamine P1 family.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
UOM:  1 * 100 µl
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