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block+heaters+
Numéro de catalogue:
(BOSSBS-2948R-A555)
Fournisseur:
Bioss
Description:
ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. It is alternatively referred to as the RNase L inhibitor as it functions to block the activity of ribonuclease L(referenced from entrez gene).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6468R-HRP)
Fournisseur:
Bioss
Description:
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6477R-A647)
Fournisseur:
Bioss
Description:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5324R-A647)
Fournisseur:
Bioss
Description:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5324R-FITC)
Fournisseur:
Bioss
Description:
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM:
1 * 100 µl
Fournisseur:
Biotium
Description:
Fibronectin is a dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.
Fournisseur:
Thermo Fisher Scientific
Description:
En PP. Conçue pour la réalisation de PCR à haut débit, cette plaque 384 puits est compatible avec la majorité des instruments pour PCR et de séquençage sur 384 puits. La jupe complète et le plateau rigide permettent de minimiser la distorsion lors de la PCR, ce qui permet une utilisation avec les systèmes robotisés.
Numéro de catalogue:
(391-1293)
Fournisseur:
VWR Collection
Description:
Ce film, en vinyle blanc de 240 µm d'épaisseur avec adhésif, convient aux microplaques blanches. Les propriétés de réflexion de la lumière de ce film, dans le cas où il est utilisé pour le scellage de plaques à fond transparent, optimise la sensibilité des tests de bioluminescence et chimiluminescence avec luminomètres à lecture par le dessous. Le film blanc sert également de matrice de support pour les applications en microscopie des échantillons perforés des plaques de filtration.
UOM:
1 * 50 ST
Numéro de catalogue:
(BOSSBS-12877R)
Fournisseur:
Bioss
Description:
Predominantly localized to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumorigenesis.
UOM:
1 * 100 µl
Fournisseur:
Cayman Chemical
Description:
Nortriptyline is a tricyclic antidepressant that blocks norepinephrine and serotonin transporters (K<sub>D</sub>s = 4.4 and 18 nM, respectively) more potently than the dopamine transporter (K<sub>D</sub> = 1.1 µM). It also antagonises serotonin, histamine, muscarinic, and α-adrenergic receptors (K<sub>i</sub>s = 5.0, 8.5, 10, 40, and 60 nM for 5-HT<sub>2A</sub>, 5-HT<sub>2C</sub>, H<sub>1</sub>, α<sub>1</sub>, and M<sub>1</sub> receptors, respectively)<B>.</B>
Numéro de catalogue:
(730-0340)
Fournisseur:
VWR Collection
Description:
L’unité d’électrophorèse horizontale sur gel de format à 96 puits est compatible avec les pipettes multicanaux à 8 canaux, et correspond à la configuration de plaque à 96 puits standard.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-5165R-A555)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5166R-A350)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3932R-A680)
Fournisseur:
Bioss
Description:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9687R-A750)
Fournisseur:
Bioss
Description:
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream Signalling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct Signalling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukaemia. Alternatively spliced transcript variants have been found for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3932R-A555)
Fournisseur:
Bioss
Description:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
UOM:
1 * 100 µl
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