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Numéro de catalogue: (BOSSBS-1434R-A488)

Fournisseur:  Bioss
Description:   IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1434R-A555)

Fournisseur:  Bioss
Description:   IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1434R-A647)

Fournisseur:  Bioss
Description:   IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12188R-A350)

Fournisseur:  Bioss
Description:   Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4568R-A555)

Fournisseur:  Bioss
Description:   EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4568R-A350)

Fournisseur:  Bioss
Description:   EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2010R-A680)

Fournisseur:  Bioss
Description:   EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2010R-A488)

Fournisseur:  Bioss
Description:   EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2009R-A680)

Fournisseur:  Bioss
Description:   EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11788R-A555)

Fournisseur:  Bioss
Description:   The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2921R-A350)

Fournisseur:  Bioss
Description:   Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2903R)

Fournisseur:  Bioss
Description:   ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation and decreased lysine 9 methylation of histone H3.
UOM:  1 * 100 µl
Fournisseur:  VWR Chemicals
Description:   Biological buffers are useful for cell culture <i>in vitro</i>, enzyme assays, and some electrophoretic applications at physiological pH.
Fournisseur:  VWR Collection
Description:   Rouleaux de film de scellage adhésif montés sur matériaux plastiques, à utiliser avec les soudeurs automatisés haut débit pour microplaques.
Numéro de catalogue: (BOSSBS-10092R-A350)

Fournisseur:  Bioss
Description:   PLAG1 is a transcription factor whose activation results in upregulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with upregulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.
UOM:  1 * 100 µl
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