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Numéro de catalogue: (BOSSBS-2604R-A555)

Fournisseur:  Bioss
Description:   Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6594R-A555)

Fournisseur:  Bioss
Description:   May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0743R-A680)

Fournisseur:  Bioss
Description:   Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Red blood cells are the most common type of blood cell and are the vertebrate body's principal means of delivering oxygen from the lungs or gills to body tissues via the blood.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5863R-CY5)

Fournisseur:  Bioss
Description:   Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4166R-A488)

Fournisseur:  Bioss
Description:   Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1971R-CY7)

Fournisseur:  Bioss
Description:   Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA (MCCPA), the expression of latexin in rat mast cells has not previously been confirmed.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1971R-CY5.5)

Fournisseur:  Bioss
Description:   Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA (MCCPA), the expression of latexin in rat mast cells has not previously been confirmed.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1971R)

Fournisseur:  Bioss
Description:   Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA (MCCPA), the expression of latexin in rat mast cells has not previously been confirmed.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2551R-CY3)

Fournisseur:  Bioss
Description:   Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2420R-CY7)

Fournisseur:  Bioss
Description:   Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2420R-CY3)

Fournisseur:  Bioss
Description:   Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7666R)

Fournisseur:  Bioss
Description:   MGC13096, also known as PDCD2L, might play a role in apoptosis given evidence that over expression attenutates TNF alpha release in Daudi cells anad restrained proliferation of HEK293T cells.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1529R-A488)

Fournisseur:  Bioss
Description:   Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilisation. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
UOM:  1 * 100 µl
Fournisseur:  Tonbo Biosciences
Description:   The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.
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