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cell+culture+flasks
Numéro de catalogue:
(BOSSBS-3605R-A647)
Fournisseur:
Bioss
Description:
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. The presence of TEAD transcription factors are required for it to stimulate gene expression, cell growth, anchorage-independent growth, and epithelial mesenchymal transition (EMT) induction. Isoform 2 and isoform 3 can activate the C-terminal fragment (CTF) of ERBB4 (isoform 3).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3605R-HRP)
Fournisseur:
Bioss
Description:
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. The presence of TEAD transcription factors are required for it to stimulate gene expression, cell growth, anchorage-independent growth, and epithelial mesenchymal transition (EMT) induction. Isoform 2 and isoform 3 can activate the C-terminal fragment (CTF) of ERBB4 (isoform 3).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2490R-CY3)
Fournisseur:
Bioss
Description:
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2490R-CY5.5)
Fournisseur:
Bioss
Description:
Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6933R-CY5.5)
Fournisseur:
Bioss
Description:
Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5355R-A680)
Fournisseur:
Bioss
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2551R-CY5)
Fournisseur:
Bioss
Description:
Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13625R-CY5)
Fournisseur:
Bioss
Description:
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13625R-CY3)
Fournisseur:
Bioss
Description:
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2521R-A680)
Fournisseur:
Bioss
Description:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5729R-A488)
Fournisseur:
Bioss
Description:
Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5729R-A350)
Fournisseur:
Bioss
Description:
Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1502R-A647)
Fournisseur:
Bioss
Description:
In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4961R-A680)
Fournisseur:
Bioss
Description:
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4961R-FITC)
Fournisseur:
Bioss
Description:
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4961R-A647)
Fournisseur:
Bioss
Description:
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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