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Fournisseur:  Shenandoah Biotechnology
Description:   Stromal cell-derived factor-1 beta (SDF-1 β), also called CXCL12b, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1 β signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes.
New Product
Fournisseur:  Biotium
Description:   CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Fournisseur:  Biotium
Description:   CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
UOM:  1 * 50 µl
Fournisseur:  Biotium
Description:   CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Numéro de catalogue: (BOSSBS-4890R-CY5.5)

Fournisseur:  Bioss
Description:   Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1944R)

Fournisseur:  Bioss
Description:   The WRCH1 protein is a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5837R-A555)

Fournisseur:  Bioss
Description:   EPDR1 is a type II transmembrane protein and is similar to two families of cell adhesion molecules, the protocadherins and ependymins. It may play a role in calcium dependent cell adhesion. There are two named isoforms.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6737R-A488)

Fournisseur:  Bioss
Description:   SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   EPDR1 is a type II transmembrane protein and is similar to two families of cell adhesion molecules, the protocadherins and ependymins. It may play a role in calcium dependent cell adhesion. There are two named isoforms.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7052R-A647)

Fournisseur:  Bioss
Description:   Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumour tissues.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1957R-A488)

Fournisseur:  Bioss
Description:   Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
UOM:  1 * 100 µl
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