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Fournisseur:  Avantor Fluid Handling
Description:   Designed with maintenance-free high-accuracy motor and a graphical interface—makes setup and operation easier than ever!
ETL listed ETL Canada listed CE Compliant
Fournisseur:  Avantor Fluid Handling
Description:   Bendable a low temperatures.
CE certificate
Fournisseur:  Avantor Fluid Handling
Description:   Connect any I/P® pump head to a 56C frame motor.
2 year warranty
Fournisseur:  Avantor Fluid Handling
Description:   Make the most of your Masterflex® piston pumps with these accessories.
Fournisseur:  Avantor Fluid Handling
Description:   Safely pump harsh chemicals.
CE certificate
Fournisseur:  Avantor Fluid Handling
Description:   Does not deteriorate with age.
CE certificate
Fournisseur:  Avantor Fluid Handling
Description:   Won't crack or oxidize.
CE certificate
Fournisseur:  Avantor Fluid Handling
Description:   Achieve high pressure and accurate, pulseless flow -- with an intuitive touch-screen interface.
UOM:  1 * 1 ST
MasterflexLive® 2 year warranty
Fournisseur:  Avantor Fluid Handling
Description:   Resists build-up and bacterial growth.
CE certificate
Numéro de catalogue: (MFLX22050-54)

Fournisseur:  Avantor Fluid Handling
Description:   Optimize performance of your Masterflex® pump.
UOM:  1 * 1 ST
Fournisseur:  Avantor Fluid Handling
Description:   No more eye strain - front shield magnifies scale 16 percent for easier readings.
Fournisseur:  Avantor Fluid Handling
Description:   Don’t sacrifice suitability for precision.
Numéro de catalogue: (BOSSBS-3804R-A750)

Fournisseur:  Bioss
Description:   Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and Recognises single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0758R)

Fournisseur:  Bioss
Description:   Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0758R-CY5)

Fournisseur:  Bioss
Description:   Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM:  1 * 100 µl
Fournisseur:  Avantor Fluid Handling
Description:   No BPA or phthalates—environmentally responsible, more sustainable, and safer.
CE certificate
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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