Imprimer
Votre recherche pour:
11 238 les résultats ont été trouvés
Protéines et Peptides
Numéro de catalogue:
(PRSI92-722)
Fournisseur:
ProSci Inc.
Description:
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence, a 126 aa extracellular domain (ECD) with one Ig-like V-type domain, a 21 aa transmembrane (TM) sequence, and a 41 aa cytoplasmic sequence. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4001P)
Fournisseur:
ProSci Inc.
Description:
APH1 peptide is used for blocking the activity of APH1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7439P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the carboxy terminus of B2M.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5851P)
Fournisseur:
ProSci Inc.
Description:
SCRN2 peptide is used for blocking the activity of SCRN2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI40-606)
Fournisseur:
ProSci Inc.
Description:
M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant rat M-CSF is a 18.1 kDa homodimeric protein containing two 155 amino acid polypeptide subunits.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-252)
Fournisseur:
ProSci Inc.
Description:
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces parthanatos i.e., caspase-independent fragmentation of chromosomal DNA. AIFM1 interacts with EIF3G, and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. It binds to DNA in a sequence-independent manner and plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-253)
Fournisseur:
ProSci Inc.
Description:
Uroporphyrinogen decarboxylase (UROD), is an enzyme of the heme biosynthetic pathway which belongs to the uroporphyrinogen decarboxylase family. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. UROD is a homodimeric enzyme that catalyzes the fifth step in heme biosynthesis: the elimination of carboxyl groups from the four acetate side chains of uroporphyrinogen III to yield coproporphyrinogen III. Defects in UROD are the cause of familial porphyria cutanea tarda (FPCT) and hepatoerythropoietic porphyria (HEP).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6409P)
Fournisseur:
ProSci Inc.
Description:
SPRYD5 peptide is used for blocking the activity of SPRYD5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-570)
Fournisseur:
ProSci Inc.
Description:
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and it contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6217P)
Fournisseur:
ProSci Inc.
Description:
GLS2 peptide is used for blocking the activity of GLS2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6221P)
Fournisseur:
ProSci Inc.
Description:
LRRFIP2 peptide is used for blocking the activity of LRRFIP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6219P)
Fournisseur:
ProSci Inc.
Description:
LRRFIP1 peptide is used for blocking the activity of LRRFIP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6211P)
Fournisseur:
ProSci Inc.
Description:
BAPX1 peptide is used for blocking the activity of BAPX1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-468)
Fournisseur:
ProSci Inc.
Description:
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7101P)
Fournisseur:
ProSci Inc.
Description:
FRL1 Peptide is used for blocking the activity of FRL1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4475P)
Fournisseur:
ProSci Inc.
Description:
Slitrk5 peptide is used for blocking the activity of Slitrk5 antibody.
UOM:
1 * 50 µG
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||
Vue liste
