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Protéines et Peptides
Numéro de catalogue:
(PRSI6087P)
Fournisseur:
ProSci Inc.
Description:
ZIP4 peptide is used for blocking the activity of ZIP4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-715)
Fournisseur:
ProSci Inc.
Description:
Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signalling in osteoblastic cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-001)
Fournisseur:
ProSci Inc.
Description:
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3895P)
Fournisseur:
ProSci Inc.
Description:
TRPC3 peptide is used for blocking the activity of TRPC3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-215)
Fournisseur:
ProSci Inc.
Description:
FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6031P)
Fournisseur:
ProSci Inc.
Description:
PIWI-L2 peptide is used for blocking the activity of PIWI-L2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4573P)
Fournisseur:
ProSci Inc.
Description:
NPTX2 peptide is used for blocking the activity of NPTX2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4557P)
Fournisseur:
ProSci Inc.
Description:
Ambra1 peptide is used for blocking the activity of Ambra1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4555P)
Fournisseur:
ProSci Inc.
Description:
Ambra1 peptide is used for blocking the activity of Ambra1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4571P)
Fournisseur:
ProSci Inc.
Description:
ELOVL6 peptide is used for blocking the activity of ELOVL6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-980)
Fournisseur:
ProSci Inc.
Description:
Prefoldin Subunit 4 (PFDN4) is a heterohexameric chaperone protein that belongs to the prefoldin subunit beta family. The complex of PFDN4, consisting of two PFD-alpha type and four PFD-beta type subunits, forms a double beta barrel assembly with six protruding coiled-coils. PFDN4 binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-976)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate. The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6389P)
Fournisseur:
ProSci Inc.
Description:
ATAD3B peptide is used for blocking the activity of ATAD3B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6387P)
Fournisseur:
ProSci Inc.
Description:
ATAD3A peptide is used for blocking the activity of ATAD3A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5015P)
Fournisseur:
ProSci Inc.
Description:
SPG11 peptide is used for blocking the activity of SPG11 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-410)
Fournisseur:
ProSci Inc.
Description:
Insulin-like growth factor 1 (IGF-1) is also known as somatomedin C, IGF1A, IGFI, sulfation factor, and is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons. IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. IGF-1 binds to at least two cell surface receptors: the Insulin-like growth factor 1 receptor, abbreviated as "IGF1R", and the insulin receptor. The IGF-1 receptor seems to be the "physiologic" receptor - it binds IGF-1 at significantly higher affinity than the IGF-1 that is bound to the insulin receptor. Like the insulin receptor, the IGF-1 receptor is a receptor tyrosine kinase - meaning it signals by causing the addition of a phosphate molecule on particular tyrosines. Its primary action is mediated by binding to its specific receptor IGF1R, present on many cell types in many tissues. Binding to the IGF1R, a receptor tyrosine kinase, initiates intracellular signaling; IGF-1 is one of the most potent natural activators of the AKT signaling pathway, a stimulator of cell growth and proliferation, and a potent inhibitor of programmed cell death. Insulin-like growth factor 1 has been shown to bind and interact with all the IGF-1 Binding Proteins (IGFBPs), of which there are six (IGFBP1-6). Specific references are provided for interactions with IGFBP3, IGFBP4 and IGFBP7.
UOM:
1 * 1 EA
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