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Bioss
Numéro de catalogue:
(BOSSBS-15412R)
Fournisseur:
Bioss
Description:
Anti-HAPLN4 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15422R)
Fournisseur:
Bioss
Description:
HCAP G is a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13730R)
Fournisseur:
Bioss
Description:
Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15421R)
Fournisseur:
Bioss
Description:
Anti-HCA25a Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6240R)
Fournisseur:
Bioss
Description:
TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6248R)
Fournisseur:
Bioss
Description:
This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3856R)
Fournisseur:
Bioss
Description:
Anti-HSD17B2 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13530R)
Fournisseur:
Bioss
Description:
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interacts with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling, along with involvement in many pathological conditions. GPR31 (G-protein coupled receptor 31) is a 319 amino acid orphan receptor that localizes to the cell membrane. GPR31 shares 25-33% homology with members of the chemokine, purino and somatostatin receptor gene families.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8408R)
Fournisseur:
Bioss
Description:
Anti-GK5 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8419R)
Fournisseur:
Bioss
Description:
Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8423R)
Fournisseur:
Bioss
Description:
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL1 (bactericidal/permeability-increasing protein-like 1) is a 458 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL1 is primarily expressed at low levels in tonsil tissue, it has been found to be upregulated in hypertrophic tonsils, suggesting that it may play a role in the pathogenesis of inflamed disease tissue.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8409R)
Fournisseur:
Bioss
Description:
GLB1L3 is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8425R)
Fournisseur:
Bioss
Description:
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL3 (Bactericidal/permeability-increasing protein-like 3) is a 453 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL3 is primarily expressed at low levels in tonsils, it has been found to be upregulated in hypertrophic tonsil tissue, suggesting that it may play a role in the pathogenesis of inflamed disease tissue.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8424R)
Fournisseur:
Bioss
Description:
Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL2 (Bactericidal/permeability-increasing protein-like 2) is a 507 amino acid secreted protein that contains the family’s common conserved feature of two cysteine residues that are critical for protein function. While BPIL2 is expressed in the basal layer of inflamed epidermis from psoriasis patients, it is not detected in normal skin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8426R)
Fournisseur:
Bioss
Description:
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8444R)
Fournisseur:
Bioss
Description:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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