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Bioss
Numéro de catalogue:
(BOSSBS-11639R-HRP)
Fournisseur:
Bioss
Description:
APPBP2 is a hydrophilic, microtubule binding protein that functions in the trafficking of Beta-Amyloid precursor protein. It is expressed in a variety of cell types and localizes to the cytoplasm. APPBP2 shares homology with kinesin light chain. It consists of a coiled-coil domain, PKC phosphorylation sites, four imperfect C-terminal tandem repeats, eight tetratricopeptide repeats and N- and C-terminal globular structures. APPBP2 recognizes and binds to the basolateral sorting sequence (BaSS) present in the cytoplasmic domain of the Beta-Amyloid precursor protein. In addition, APPBP2 interacts with the androgen receptor and suppresses androgen signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8053R-FITC)
Fournisseur:
Bioss
Description:
KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0356R-A750)
Fournisseur:
Bioss
Description:
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5938R-A350)
Fournisseur:
Bioss
Description:
LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13282R-A647)
Fournisseur:
Bioss
Description:
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2077R-A350)
Fournisseur:
Bioss
Description:
AMP deaminase plays a critical role in energy metabolism.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2077R-CY5.5)
Fournisseur:
Bioss
Description:
AMP deaminase plays a critical role in energy metabolism.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5938R-HRP)
Fournisseur:
Bioss
Description:
LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5938R-CY3)
Fournisseur:
Bioss
Description:
LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2077R-CY3)
Fournisseur:
Bioss
Description:
AMP deaminase plays a critical role in energy metabolism.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5938R-A647)
Fournisseur:
Bioss
Description:
LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13581R-A750)
Fournisseur:
Bioss
Description:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. localised to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6558R-CY5.5)
Fournisseur:
Bioss
Description:
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6299R-CY3)
Fournisseur:
Bioss
Description:
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15399R-HRP)
Fournisseur:
Bioss
Description:
H2A1J.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15399R-CY7)
Fournisseur:
Bioss
Description:
H2A1J.
UOM:
1 * 100 µl
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