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Bioss
Numéro de catalogue:
(BOSSBS-0214R-A647)
Fournisseur:
Bioss
Description:
Inhibitor of the caspase-activated DNase (DFF40).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0155R-CY5.5)
Fournisseur:
Bioss
Description:
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12950R-A555)
Fournisseur:
Bioss
Description:
TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12950R-CY5)
Fournisseur:
Bioss
Description:
TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12950R-CY7)
Fournisseur:
Bioss
Description:
TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10288R-CY5)
Fournisseur:
Bioss
Description:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6716R-A555)
Fournisseur:
Bioss
Description:
Uricase catalyzes the oxidation of uric acid to 5 hydroxyisourate which spontaneously decomposes to form allantoin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-14545R-A750)
Fournisseur:
Bioss
Description:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6715R-A680)
Fournisseur:
Bioss
Description:
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9411R-FITC)
Fournisseur:
Bioss
Description:
TSPAN2 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. TSPAN2 may play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12343R-FITC)
Fournisseur:
Bioss
Description:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3875R-CY5.5)
Fournisseur:
Bioss
Description:
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1684R-A680)
Fournisseur:
Bioss
Description:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11921R-A680)
Fournisseur:
Bioss
Description:
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11921R-HRP)
Fournisseur:
Bioss
Description:
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8488R-CY5.5)
Fournisseur:
Bioss
Description:
FNDC8
UOM:
1 * 100 µl
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