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Bioss
Numéro de catalogue:
(BOSSBS-5463R-A750)
Fournisseur:
Bioss
Description:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarisation of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15530R-A488)
Fournisseur:
Bioss
Description:
IBP160.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3728R-FITC)
Fournisseur:
Bioss
Description:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3729R-CY5.5)
Fournisseur:
Bioss
Description:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7945R-FITC)
Fournisseur:
Bioss
Description:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription. There are 2 isoforms produced by alternative splicing.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7945R-CY5.5)
Fournisseur:
Bioss
Description:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription. There are 2 isoforms produced by alternative splicing.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7745R-A350)
Fournisseur:
Bioss
Description:
Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3729R-FITC)
Fournisseur:
Bioss
Description:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7945R-HRP)
Fournisseur:
Bioss
Description:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro). It may activate transcription. There are 2 isoforms produced by alternative splicing.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15530R-CY3)
Fournisseur:
Bioss
Description:
IBP160.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7945R-A680)
Fournisseur:
Bioss
Description:
ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (<i>in vitro</i>). It may activate transcription. There are 2 isoforms produced by alternative splicing.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9479R-A647)
Fournisseur:
Bioss
Description:
SMARCD3, is a member of the SMARCD family and contains one SWIB domain. Two isoforms, isoform 1 and isoform 2 exist due to alternative splicing events. Both isoforms are expressed in placenta, salivary gland, kidney, brain, trachea, uterus, prostate, testis, thyroid, spleen and heart, while isoform 1 is also expressed in adipose tissue and skeletal muscle. Localizing to the nucleus, SMARCD3 is a component of the ATP-dependent chromatin remodeling complex SNF/SWI and is believed to play a role in nucleosome remodeling. SMARCD3 also plays an important role in the regulation of muscle development. In mice, the silencing of the gene en-coding SMARCD3 leads to defects in heart morphogenesis. In addition, both isoforms of SMARCD3 directly interact with and function as coactivators for several transcription factors.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9478R-HRP)
Fournisseur:
Bioss
Description:
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12503R-CY3)
Fournisseur:
Bioss
Description:
APPBP1 is a member of the ubiquitin-activating E1 family. In fetal tissues APPBP1 is widely expressed and in adult tissues it is expressed throughout the brain. APPBP1 is a cell membrane associated protein and functions as the regulatory subunit in a heterodimer with UBA3. The APPBP1/UBA3 complex binds to and activates NEDD8, a ubiquitin-like protein involved in signal transduction, cell proliferation and development. This suggests that APPBP1 affects a variety of cellular functions. In addition, APPBP1 is essential for cell cycle progression through the S/M checkpoint. More specifically, it inhibits the entry into S phase and promotes entry into M phase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15478R-A488)
Fournisseur:
Bioss
Description:
HHLA1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5581R-A680)
Fournisseur:
Bioss
Description:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
UOM:
1 * 100 µl
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