Bioss
Numéro de catalogue:
(BOSSBS-3309R-CY7)
Fournisseur:
Bioss
Description:
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10421R-A647)
Fournisseur:
Bioss
Description:
Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. (referenced from swissprot)
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4848R-CY3)
Fournisseur:
Bioss
Description:
RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. May be involved in the control of cellular proliferation and/or differentiation (By similarity). Heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer and through the Runt domain.DNA-binding is increased by heterodimerization. Interacts with TLE1 and SUV39H1, Subcellular location in Nucleus.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0300R-CY7)
Fournisseur:
Bioss
Description:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0300R-CY5)
Fournisseur:
Bioss
Description:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12125R-HRP)
Fournisseur:
Bioss
Description:
The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5757R-A555)
Fournisseur:
Bioss
Description:
FAM13B1
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2143R-HRP)
Fournisseur:
Bioss
Description:
Batroxobin
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5951R-CY5)
Fournisseur:
Bioss
Description:
Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5951R-HRP)
Fournisseur:
Bioss
Description:
Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-14046R-CY7)
Fournisseur:
Bioss
Description:
May play a role in polarized cells morphogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-14046R-A647)
Fournisseur:
Bioss
Description:
May play a role in polarized cells morphogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-14046R-HRP)
Fournisseur:
Bioss
Description:
May play a role in polarized cells morphogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6625R-A350)
Fournisseur:
Bioss
Description:
Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2809R-A488)
Fournisseur:
Bioss
Description:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8560R-FITC)
Fournisseur:
Bioss
Description:
Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.
UOM:
1 * 100 µl
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