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Bioss
Numéro de catalogue:
(BOSSBS-7960R-A750)
Fournisseur:
Bioss
Description:
AMN1.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13588R-CY7)
Fournisseur:
Bioss
Description:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 575 (ZNF575) is a 245 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF575 contains six C2H2-type zinc fingers through which it is thought to be involved in DNA-binding and transcriptional regulation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0272R-CY5)
Fournisseur:
Bioss
Description:
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2184R-A488)
Fournisseur:
Bioss
Description:
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2183R-A680)
Fournisseur:
Bioss
Description:
Plays a major role in tight junction-specific oblitreation of the intercellular space, through calcium-independent cell-adhesion activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0273R-A488)
Fournisseur:
Bioss
Description:
icotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Fisfatin) Catalyzes the condensation of nicotinamide with5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues. Subcellular Location is in Cytoplasm. Belongs to the NAPRTase family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13342R-HRP)
Fournisseur:
Bioss
Description:
GFPT2 (glutamine-fructose-6-phosphate transaminase 2), also known as D-fructose-6-phosphate amidotransferase 2 or hexosephosphate aminotransferase 2, is a 682 amino acid protein and isoenzyme of GFAT1, the first and rate-limiting enzyme for the entry of glucose into the hexosamine biosynthetic pathway (HBP), which is a relatively minor branch of glycolysis. Expressed in spinal cord, heart and placenta, GFAT2 regulates glucose entry into the HBP and likely controls the availability of precursors for N- and O-linked protein glycosylation. Containing one glutamine amidotransferase type-2 domain and two SIS domains. GFAT2 is encoded by a gene that maps to human chromosome 5q35.3. GFAT2 gene variants have been linked to type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13343R-A350)
Fournisseur:
Bioss
Description:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6240R-A488)
Fournisseur:
Bioss
Description:
TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0874R-CY7)
Fournisseur:
Bioss
Description:
The DEK gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA which then induces positive supercoils into closed circular DNA, and is also involved during mRNA processing in splice site selection. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0874R-A647)
Fournisseur:
Bioss
Description:
The DEK gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA which then induces positive supercoils into closed circular DNA, and is also involved during mRNA processing in splice site selection. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2388R-A555)
Fournisseur:
Bioss
Description:
Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6040R-CY3)
Fournisseur:
Bioss
Description:
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6825R-FITC)
Fournisseur:
Bioss
Description:
MAGEB6
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2943R-A350)
Fournisseur:
Bioss
Description:
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6179R-FITC)
Fournisseur:
Bioss
Description:
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
UOM:
1 * 100 µl
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