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ProSci Inc.
Numéro de catalogue:
(PRSI5359)
Fournisseur:
ProSci Inc.
Description:
Swine H1N1 Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2'-5'OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5361)
Fournisseur:
ProSci Inc.
Description:
Seasonal H1N1 Nucleocapsid Protein Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP), thought to control whether mRNA or cRNA is produced. The nucleoprotein (NP), which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses. It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently. This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-851)
Fournisseur:
ProSci Inc.
Description:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4203P)
Fournisseur:
ProSci Inc.
Description:
Presenilin1 peptide is used for blocking the activity of presenilin1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4119P)
Fournisseur:
ProSci Inc.
Description:
STIM1 peptide is used for blocking the activity of STIM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI54-201)
Fournisseur:
ProSci Inc.
Description:
Anti-PYY Chicken Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI71-236)
Fournisseur:
ProSci Inc.
Description:
Anti-TAOK1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-821)
Fournisseur:
ProSci Inc.
Description:
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7698)
Fournisseur:
ProSci Inc.
Description:
FUNCTION: Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein found in plasma. Four possible functions are ferroxidase activity, amine oxidase activity, copper transport and homeostasis, and superoxide dismutase activity.
DISEASE: Ceruloplasmin levels are decreased in Wilson disease, in which copper cannot be incorporated into ceruloplasmin in liver because of defects in the copper-transporting ATPase 2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXW-7704)
Fournisseur:
ProSci Inc.
Description:
VLDL transports hepatic synthesized triglycerides and cholesterol. May counteract inhibitory effect of glucocorticoids on arachidonic acid release and prostaglandin I2 formation in vascular smooth muscle cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXW-7735)
Fournisseur:
ProSci Inc.
Description:
FUNCTION: Receptor for the C-X-C chemokine SDF-1. Transduces a signal by increasing the intracellular calcium ions level. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodelling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a primary receptor for some HIV-2 isolates and as a coreceptor with CD4 for HIV-1 X4 viruses (lymphocyte-tropic HIV-1 viruses, also called syncytium-inducing (SI) strains). Promotes Env-mediated fusion of the virus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-840)
Fournisseur:
ProSci Inc.
Description:
The 2;5 chromosomal translocation is frequently associated with anaplastic large cell lymphomas (ALCLs). The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5. A recent study shows that the product of the NPM-ALK fusion gene is oncogenic. The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-500)
Fournisseur:
ProSci Inc.
Description:
HNRPUL1 is a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells.This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Four transcript variants encoding different isoforms have been found for this gene. Another variant has also been found, but its full-length nature has not been determined.This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Four transcript variants encoding different isoforms have been found for this gene. Another variant has also been found, but its full-length nature has not been determined.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-121)
Fournisseur:
ProSci Inc.
Description:
C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-708)
Fournisseur:
ProSci Inc.
Description:
Anti-GPM6A Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-199)
Fournisseur:
ProSci Inc.
Description:
Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA and has been shown to interact with IPO13. EIF1AX contains one S1-like domain and seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
UOM:
1 * 50 µG
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