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ProSci Inc.
Numéro de catalogue:
(PRSI55-334)
Fournisseur:
ProSci Inc.
Description:
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI96-215)
Fournisseur:
ProSci Inc.
Description:
CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI55-777)
Fournisseur:
ProSci Inc.
Description:
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM].
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-695)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-770)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-765)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-774)
Fournisseur:
ProSci Inc.
Description:
May be involved in transcriptional regulation.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI55-772)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-698)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI60-699)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-841)
Fournisseur:
ProSci Inc.
Description:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-853)
Fournisseur:
ProSci Inc.
Description:
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-857)
Fournisseur:
ProSci Inc.
Description:
The specific function of this protein remains unknown. There are 3 named isoforms.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI56-865)
Fournisseur:
ProSci Inc.
Description:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI61-811)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI62-740)
Fournisseur:
ProSci Inc.
Description:
For FACS starting dilution is: 1:25. For WB starting dilution is: 1:2000.
UOM:
1 * 400 µl
New Product
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