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Numéro de catalogue:
(72-8042-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(35-8065-M002)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Mouse IgM (mu chain) - Affinity Pure, FITC Conjugate
UOM:
1 * 2 mg
Numéro de catalogue:
(35-8068-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Rabbit IgG (H&L) - Affinity Pure, FITC Conjugate, min x w/ bovine, goat, human, mouse or rat IgG or serum
UOM:
1 * 1 mg
Numéro de catalogue:
(35-8066-M002)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Mouse IgM (mu chain) - Affinity Pure, FITC Conjugate, min x w/human IgG or serum proteins
UOM:
1 * 2 mg
Numéro de catalogue:
(35-8077-M002)
Fournisseur:
Tonbo Biosciences
Description:
Rabbit anti-Mouse IgG (H&L) - Affinity Pure, FITC Conjugate, min x w/human serum proteins
UOM:
1 * 2 mg
Fournisseur:
Tonbo Biosciences
Description:
The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The RM4-5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the RM4-5 antibody and an alternative antibody, Anti-Mouse CD4 clone GK1.5, will compete for binding, i.e. RM4-5 antibody is able to block GK1.5 antibody binding to cells. In contrast, RM4-5 antibody does not block the binding of Anti-Mouse CD4 clone RM4-4 to cells.
Numéro de catalogue:
(22-8067-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Rabbit IgG (H&L) - Affinity Pure, Alkaline Phosphatase Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(72-8097-M001)
Fournisseur:
Tonbo Biosciences
Description:
Donkey anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate
UOM:
1 * 1 mg
Numéro de catalogue:
(72-8104-M001)
Fournisseur:
Tonbo Biosciences
Description:
Goat anti-Rat IgG (H&L) - Affinity Pure, HRP Conjugate
UOM:
1 * 1 mg
Fournisseur:
Tonbo Biosciences
Description:
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The GK1.5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the GK1.5 antibody and an alternative antibody, Anti-Mouse CD4 clone RM4-5, will "compete" for binding, i.e. RM4-5 is able to block GK1.5 binding to cells. In contrast, the Anti-Mouse CD4 clone RM4-4 does not block binding of the GK1.5 antibody to cells (Arora S et al. 2006. Infect. Immun. 74: 4339-4348). The GK1.5 antibody is also reported to be cross-reactive with Syrian hamster CD4.
Fournisseur:
Tonbo Biosciences
Description:
The 2.4G2 antibody is specific for a common epitope found in the extracellular regions of mouse Fc-receptors Fc-gamma II (CD32) and Fc-gamma III (CD16). These receptors are expressed by B cells, monocytes, macrophages, NK cells, dendritic cells, and neutrophils.
Numéro de catalogue:
(TNB-1213-L150)
Fournisseur:
Tonbo Biosciences
Description:
Tonbo Biosciences Foxp3 / Transcription Factor Staining Buffer Kit contains specially formulated buffers and solutions for optimal resolution and low background in your analysis of nuclear antigens by flow cytometry
UOM:
1 * 150 mL
Fournisseur:
Tonbo Biosciences
Description:
The L243 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes, activated NK cells, monocytes, macrophages, other antigen presenting cells and progenitor cells. The L243 antibody is specific to an epitope on the alpha subunit of the heterodimeric HLA-DR protein and binds a different epitope than the LN3 antibody clone. It does not cross-react with HLA-DP or HLA-DQ. This antibody is reported to be cross-reactive with non-human primates including Chimpanzee, Cynomolgus, Rhesus and Baboon. Please choose the appropriate format for each application.
Fournisseur:
Tonbo Biosciences
Description:
The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.
Fournisseur:
Tonbo Biosciences
Description:
The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB, CD45RO and others. The HI100 antibody is widely used as a marker for human CD45RA expression on naive and activated T cells, B cells, and monocytes.
Fournisseur:
Tonbo Biosciences
Description:
The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.
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