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Understanding monoclonal antibody aggregate behaviour impacting chromatographic process efficiency

Webinar

On demand

Replay

As titer from upstream increases, capacity of the resins is more of important factor to drive process efficiency and impurities like aggregate reduces the capacity of monomer significantly. In this presentation, we will show the impact of aggregate on the capacity and efficiency of chromatography steps such as protein A, ion-exchange or HIC (hydrophobic interaction) columns along with use of additive and selective resins to increase product purity and process efficiency.

This presentation was given during Bioprocessing Summit Virtual, August 16-19, 2021