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Anticorps
Fournisseur:
Biotium
Description:
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
Numéro de catalogue:
(BNUM0205-50)
Fournisseur:
Biotium
Description:
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
UOM:
1 * 50 µl
Numéro de catalogue:
(USBI138502)
Fournisseur:
US Biological
Description:
Anti-Carcinoembryonic Antigen Mouse Monoclonal Antibody [clone: COL-1]
UOM:
1 * 20 µG
Numéro de catalogue:
(USBI036620-FITC)
Fournisseur:
US Biological
Description:
Anti-HLA-DPA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI042753-AP)
Fournisseur:
US Biological
Description:
Anti-TEX261 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI037472-APC)
Fournisseur:
US Biological
Description:
Anti-UHMK1 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIA1334-36N)
Fournisseur:
US Biological
Description:
Anti-ALDH5A1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(USBI043759-APC)
Fournisseur:
US Biological
Description:
Anti-VIPR2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI037477-PE)
Fournisseur:
US Biological
Description:
Anti-KIT Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIA1334-34A-BIOT)
Fournisseur:
US Biological
Description:
Anti-ALDH2 Rabbit Polyclonal Antibody (Biotin)
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI043759-PE)
Fournisseur:
US Biological
Description:
Anti-VIPR2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI043759-AP)
Fournisseur:
US Biological
Description:
Anti-VIPR2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Fournisseur:
Biotium
Description:
Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
Fournisseur:
Biotium
Description:
MAb HSA133 stains human liver canaliculi and a subset of hepatocellular carcinomas. In frozen sections, it stains liver canaliculi strongly and may be used as a marker of this hepatic substructure. Cell preparations of hepatocellular carcinoma biopsies and cell lines are found to bind this MAb on the cell surface. HSA133 strongly stains liver canaliculi and hepatic carcinoma cells using frozen sections or paraformaldehyde fixed cell preparations.
Fournisseur:
Biotium
Description:
This MAb reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This MAb is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
Fournisseur:
Biotium
Description:
Reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
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