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Anticorps
Numéro de catalogue:
(BOSSBS-10021R-HRP)
Fournisseur:
Bioss
Description:
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6273R-CY7)
Fournisseur:
Bioss
Description:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6273R-A647)
Fournisseur:
Bioss
Description:
Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2686R-CY5)
Fournisseur:
Bioss
Description:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10009R-HRP)
Fournisseur:
Bioss
Description:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1000R-CY3)
Fournisseur:
Bioss
Description:
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13155R-A680)
Fournisseur:
Bioss
Description:
Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5005R-A647)
Fournisseur:
Bioss
Description:
PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. It has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. There are two named isoforms.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5743R-A350)
Fournisseur:
Bioss
Description:
CDKN3 is a second dual specificity phosphatase that interacts with cyclin dependent kinases.The ability of CDKN3 to bind multiple cyclin-dependent kinases suggests that it may be a critical control element in cell cycle regulation, presumably by regulating the phosphorylation state of a Cdk or Cdk-associated protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5743R-FITC)
Fournisseur:
Bioss
Description:
CDKN3 is a second dual specificity phosphatase that interacts with cyclin dependent kinases.The ability of CDKN3 to bind multiple cyclin-dependent kinases suggests that it may be a critical control element in cell cycle regulation, presumably by regulating the phosphorylation state of a Cdk or Cdk-associated protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8155R-HRP)
Fournisseur:
Bioss
Description:
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3794R-CY7)
Fournisseur:
Bioss
Description:
Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1672R-A555)
Fournisseur:
Bioss
Description:
Duck plague (DP) is an acute contagious disease that is highly lethal in all ages of birds from the order Anseriforms (ducks, geese, and swans). The characterization of duck plague is tissue hemorrhage, digestive mucosal eruptions lesions of lymphoid organs and degenerative changes in parenchymatous organs. Duck plague was difficult to monitor and control, because duck plague virus established an asymptomatic carrier state in both domestic and wild waterfowls that was detectable only during the intermittent shedding period of the virus. Duck plague has resulted in significant economic losses in commercial duck industry due to high mortality rate and decreased duck egg production.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8155R-CY3)
Fournisseur:
Bioss
Description:
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3851R-A350)
Fournisseur:
Bioss
Description:
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1635R-A555)
Fournisseur:
Bioss
Description:
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).
UOM:
1 * 100 µl
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