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Numéro de catalogue: (BOSSBS-6463R-CY7)

Fournisseur:  Bioss
Description:   Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
UOM:  1 * 100 µl
Numéro de catalogue: (PRSI6053)

Fournisseur:  ProSci Inc.
Description:   SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
UOM:  1 * 1 EA
Fournisseur:  Honeywell Chemicals
Description:   Acide hydrobromique 48% ACS, Fluka™
Fournisseur:  AAT BIOQUEST
Description:   Le 3'-O-Azidométhyl-dUTP est un excellent élément constitutif des dNTP qui peut être utilisé pour développer des sondes de détection de l'ADN pour le séquençage de l'ADN par synthèse (SBS) et d'autres applications de biologie moléculaire.
New Product
Fournisseur:  Thermo Fisher Scientific
Description:   Pierce™ Protein A, G and A/G coated plates provide an alternative to direct, passive adsorption methods for immobilising antibodies for ELISA and other plate-based assay techniques. Available in clear for colorimetric assays, white for chemiluminescent assays, and black for fluorescent assays.
Numéro de catalogue: (PRSI28-674)

Fournisseur:  ProSci Inc.
Description:   Transcription factors containing a homeodomain play an important role in the organogenesis of vertebrates. Otx3/Dmbx1 is a member of paired class homeodomain transcription factors. Otx3/Dmbx1 represses the Otx2-mediated transactivation in the developing brain by forming heterodimer with Otx2 on the P3C (TAATCCGATTA) sequence in vitro.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-048)

Fournisseur:  ProSci Inc.
Description:   TRIM62 contains 1 RING-type zinc finger, which is probably involved in mediating protein-protein interactions. RING-type zinc finger was identified in a group of proteins with a wide range of functions such as viral replication, signal transduction, and development. But the function of TRIM62 remains unknown.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-236)

Fournisseur:  ProSci Inc.
Description:   RBMY1A1 is a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. The gene that encodes RBMY1A1 is Y-linked. RBMY1A1 may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre-mRNA splicing in the testis.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI27-594)

Fournisseur:  ProSci Inc.
Description:   BHLHB5 is a member of family of basic helix-loop-helix (bHLH) transcription factors. Members of this family have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration.
UOM:  1 * 1 EA
Fournisseur:  Thermo Fisher Scientific
Description:   Xylène (mélange d'isomères) 99% ACS
Fournisseur:  Ahlstrom-Munksjö
Description:   These syringe filters with PP housing contain prefilters specifically developed to increase the efficiency of laboratory microfiltration applications by reducing the number of steps needed to process samples and solutions with either a high particle load or a high viscosity if standard syringe filters are used.
Numéro de catalogue: (PRSI91-641)

Fournisseur:  ProSci Inc.
Description:   Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI6111)

Fournisseur:  ProSci Inc.
Description:   CXXC5 Antibody: CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI55-081)

Fournisseur:  ProSci Inc.
Description:   The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (ANSM330206085)

Fournisseur:  ANSELL MEDICAL PRODUCTS
Description:   Ce gant est doté d'un très faible niveau de protéines : seulement <50 μg/g (méthode de Lowry modifiée - EN 455-3). Cela permet de réduire considérablement les risques d'allergies de type I. Adapté pour les interventions chirurgicales.
UOM:  1 * 50 PAIRE
Numéro de catalogue: (PRSI27-744)

Fournisseur:  ProSci Inc.
Description:   FOXJ2 is a fork head factor that is expressed in many adult tissues. In the embryo, FOXJ2 expression showed a very early onset during the cleavage stages of preimplantation development. It is capable of activating transcription from promoters containing its sites
UOM:  1 * 1 EA
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