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Ace+Method+Development+Kits
Numéro de catalogue:
(BOSSBS-11988R-CY3)
Fournisseur:
Bioss
Description:
Brain-specific neurabin I (neural tissue-specific F-actin binding protein I) is highly concentrated in the synapse of developed neurons; it localizes in the growth cone lamellipodia during neuronal development (1). Suppression of endogenous neurabin in rat hippocampal neurons inhibits neurite formation (1). Neurabin I recruits active PP1 via a PP1-docking sequence; mutation of the PP1-binding motif halts filopodia and restores stress fibers in neurabin I-expressing cells (2,3). Neurabin II (Spinophilin) is ubiquitously expressed but is abundantly expressed in brain (4). Neurabin II localizes to neuronal dentritic spines, which are the specialized protrusions from dendritic shafts that receive most of the excitatory input in the CNS (5). Neurabin II may regulate dendritic spine properties as neurabin II(-) mice have increased spine density during development in vitro and exhibit altered filopodial formation in cultured cells (5). Neurabin may also play a role in glutamatergic transmission as Neurabin II(-) mice exhibit reduced long-term depression and resistance to kainate-induced seizures and neronal apoptosis (5). Neurabin II complexes with the catalytic subunit of protein phosphatase-1 (PP1) in vitro thus modulating the activity of PP1 (4).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11200R-A555)
Fournisseur:
Bioss
Description:
Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11833R-A350)
Fournisseur:
Bioss
Description:
Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9781R-A750)
Fournisseur:
Bioss
Description:
Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity).
UOM:
1 * 100 µl
Fournisseur:
Brady
Description:
Méthode sûre et efficace de condamnation des disjoncteurs européens puisqu'ils s'adaptent à la plupart des modèles actuels. Il est recommandé de les utiliser conjointement avec un cadenas pour plus de sécurité.
Fournisseur:
Avantor
Description:
Avantor® ACE® UltraCore BIO C18 are high performing solid-core (core-shell) particle columns designed for a wide range of biomolecule applications. With both 300 Å and 500 Å pore sizes available, optimum pore size can be chosen. This phase is well suited to the analysis of more hydrophilic proteins over 5 kDa molecular weight.
Fournisseur:
VWR Chemicals
Description:
Sodium carbonate ≥99.9%, AnalaR NORMAPUR® ACS, Reag. Ph. Eur. pour analyses
Numéro de catalogue:
(BOSSBS-11884R-CY5)
Fournisseur:
Bioss
Description:
The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11974R-CY7)
Fournisseur:
Bioss
Description:
In Drosophila, neuronal cell fate decisions are directed by NUMB, a signaling adapter protein with two protein-protein interaction domains, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1794R-CY5.5)
Fournisseur:
Bioss
Description:
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(ACE-MC3210)
Fournisseur:
Avantor
Description:
PEEK ¹/₃₂" microbore HPLC column inlet / outlet connectors. These column connectors are recommended for ¹/₃₂" microbore HPLC column connections. They are compatible with both capillary (360 µm OD) and ¹/₃₂" connection tubing.
UOM:
1 * 10 ST
Numéro de catalogue:
(BOSSBS-1275R-CY7)
Fournisseur:
Bioss
Description:
Transcriptional repressor that plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B-cell development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6817R-A350)
Fournisseur:
Bioss
Description:
Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8561R-A555)
Fournisseur:
Bioss
Description:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6817R-A555)
Fournisseur:
Bioss
Description:
Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
UOM:
1 * 100 µl
Fournisseur:
VWR Chemicals
Description:
Cobalt (II) chlorure hexahydraté 98-102% ACS
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