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Ace+Method+Development+Kits
Numéro de catalogue:
(BOSSBS-11293R-FITC)
Fournisseur:
Bioss
Description:
The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0817R-A350)
Fournisseur:
Bioss
Description:
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11480R-FITC)
Fournisseur:
Bioss
Description:
Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.
UOM:
1 * 100 µl
Numéro de catalogue:
(41771.36)
Fournisseur:
Thermo Scientific
Description:
Anhydride phtalique 99.0-100.2% ACS
UOM:
1 * 500 g
Numéro de catalogue:
(ENZOBMLKI5910050)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The FLUOR DE LYS®-Succinyl green, desuccinylase substrate offers a highly sensitive and convenient alternative to radiolabeled, succinylated histones or peptide/HPLC methods for the assay of desuccinylases such as SIRT5.
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(ENZOALX260158M005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of caspase-6, -8 and -10
UOM:
1 * 5 mg
New Product
Fournisseur:
Thermo Scientific
Description:
Acide sulfureux (≥ 6,0% SO₂) en solution aqueuse ACS
Numéro de catalogue:
(BOSSBS-1039R-A350)
Fournisseur:
Bioss
Description:
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6134R-A680)
Fournisseur:
Bioss
Description:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Overexpression may be associated with abnormal proliferation in human breast tissue.
UOM:
1 * 100 µl
Fournisseur:
Avantor
Description:
These high performance UHPLC columns contain high purity spherical silica.
Numéro de catalogue:
(BOSSBS-0200R-A750)
Fournisseur:
Bioss
Description:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
UOM:
1 * 100 µl
Numéro de catalogue:
(BSENM-1378-250)
Fournisseur:
Biosensis
Description:
Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Alpha-internexin is a ~66 kDa Class IV intermediate filament subunit expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
UOM:
1 * 250 µl
Numéro de catalogue:
(ENZOBMLP1340005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Caspase substrate
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(BOSSBS-10058R-CY3)
Fournisseur:
Bioss
Description:
Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10058R-CY5)
Fournisseur:
Bioss
Description:
Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0627R-A680)
Fournisseur:
Bioss
Description:
Isoform 1: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression. Isoform 2: Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.
UOM:
1 * 100 µl
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