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Ace+Method+Development+Kits
Numéro de catalogue:
(BOSSBS-2358R-CY3)
Fournisseur:
Bioss
Description:
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2358R-A555)
Fournisseur:
Bioss
Description:
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8634R-HRP)
Fournisseur:
Bioss
Description:
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate; FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription; required for ESR1 binding to the NKX2-1 promoter in breast cancer cells; binds to the RPRM promter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.
UOM:
1 * 100 µl
Numéro de catalogue:
(HT102A-1KT)
Fournisseur:
SIGMA-ALDRICH MICROSCOPY
Description:
The kit is based upon the method of Gordon and Sweets.
UOM:
1 * 1 KIT
Fournisseur:
Merck
Description:
Disponibles avec des particules de silice 2 μm optimisées, ces colonnes UHPLC basées sur Purospher® STAR RP-18e sont idéales pour des applications ultra-rapides pour lesquelles la résolution, la sensibilité et le débit de traitement des échantillons sont essentiels. Elles représentent le choix idéal pour des analyses CQ et un criblage à débit élevé, le contrôle de processus, le développement de méthodes et les applications LC/MS. En raison de leur sélectivité équilibrée, les colonnes UHPLC Purospher® STAR RP-18e couvrent presque toutes les séparations exigeantes avec des chromatogrammes sans traînée de pics. Les colonnes 3 μm Purospher® STAR RP-18e sont recommandées pour les échantillons difficiles, lorsque l'obstruction et la contre-pression posent problème.
Numéro de catalogue:
(1.17179.0001)
Fournisseur:
Merck
Description:
Carbon dioxide is an important parameter for the assessment of the surface water quality and of the corrosive behavior of water. The kit is used for water and wastewater treatments following titrimetric method.
UOM:
1 * 0,13 L
Numéro de catalogue:
(1.11148.0001)
Fournisseur:
Merck
Description:
Méthodes titrimétriques et colorimétriques MQuant®.
UOM:
1 * 200 Tests
Numéro de catalogue:
(1.01603.0001)
Fournisseur:
Merck
Description:
Phenol-free staining kit for the Gram staining method
UOM:
1 * 1 SET
Numéro de catalogue:
(1.10307.0500)
Fournisseur:
Merck
Description:
Test kit, Protéine (méthode du biuret à 546 nm), réactif en solution pour environ 250 déterminations
UOM:
1 * 500 mL
Numéro de catalogue:
(ENZOBMLKI1770005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Fluor de Lys®-SIRT1 is a fluorogenic, acetylated peptide substrate for SIRT1 (human Sirtuin 1). Based on residues 379-382 of p53 (Arg-His-Lys-Lys(Ac)), a site of regulatory acetylation by the p300 and CBP acetyltransferases (lysines 381, 382), it was the best substrate for SIRT1 from among a panel of substrates patterned on p53, histone H3, and histone H4 acetylation sites. Fluor de Lys®-SIRT1 is deacetylated by SIRT1 (BML-SE239) at a rate of more then 8-fold that of the acetylated lysine substrate, Fluor de Lys® (Prod. No. BML-KI104; acetylated substrates both at 25 µM, 500 µM NAD+). The Km of Fluor de Lys®-SIRT1 for human recombinant Sirtuin 1 is 108 µM (determined at 37°C, 500 µM NAD+). Must be used in conjunction with Fluor de Lys® Developer II (Prod. No. BML-KI176). Fluorescent signal indicates deacetylation of Lys382. Sufficient for 100-200 assays of human recombinant SIRT1 (1U/well, 50-100 µM substrate).
UOM:
1 * 1 VIA
New Product
Numéro de catalogue:
(1.15973.0002)
Fournisseur:
Merck
Description:
Nuclear staining in connective tissue staining methods
UOM:
1 * 2 ST
Numéro de catalogue:
(MDT100-1KT)
Fournisseur:
SIGMA-ALDRICH MICROSCOPY
Description:
Designed for orientation of excised surgical specimens. This method of permanently marking the margins of tissue specimens is very beneficial to surgeon and pathologists testing for skin cancer.
UOM:
1 * 1 KIT
Numéro de catalogue:
(A-127-6X1.2ML)
Fournisseur:
Merck
Description:
A multicomponent calibration kit containing acetone, ethanol, isopropanol, and methanol at concentrations of 100, 250, 500, 1000, 2000, and 4000 μg/mL. This kit is suitable for calibration of blood alcohol testing methods using GC Headspace.
UOM:
1 * 6 ST
Numéro de catalogue:
(1.11142.0001)
Fournisseur:
Merck
Description:
Méthodes titrimétriques et colorimétriques MQuant®
UOM:
1 * 400 Tests
Numéro de catalogue:
(TDF100A-1KT)
Fournisseur:
Merck
Description:
This assay determines the total dietary fiber content of food using a combination of enzymatic and gravimetric methods. Samples of dried, fat-free foods are gelatinised with heat stable α-amylase and then enzymatically digested with protease and amyloglucosidase to remove the protein and starch present in the sample.
UOM:
1 * 1 KIT
Fournisseur:
Merck
Description:
Multi-component calibration kits containing acetone, ethanol, isopropanol, and methanol varying concentrations. These kits ares suitable for calibration of blood alcohol testing methods using GC Headspace.
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