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Fournisseur:  VWR Chemicals
Description:   This CRM is intended for:
Calibration of classical volumetric analysis
Validation of analytical methods
Preparation of “working reference samples”
Detection limit and linearity studies
UOM:  1 * 1 L
New Product
Fournisseur:  TCI
Description:   (S)-2-Acetamido-3-methylbutanoic acid ≥98.0% (par HPLC, analyse par titration)
Fournisseur:  THERMO FISHER DIAGNOSTICS GMBH
Description:   Place antimicrobial susceptibility disks onto your media of choice when carrying out manual antimicrobial susceptibility testing methods using a self-tamping Thermo Scientific™ Oxoid™ antimicrobial susceptibility disk dispenser.
Numéro de catalogue: (BOSSBS-9563R-CY5.5)

Fournisseur:  Bioss
Description:   LMBR1 is a 490 amino acid multi-pass membrane protein that is widely expressed with strongest expression in heart and pancreas. Belonging to the LIMR family, LMBR1 shares 95% sequence identity with the mouse protein and may play crucial role in the evolution of limb and skeletal system. LMBR1 is critical for expression of sonic hedgehog (Shh) in the developing posterior limb bud mesenchyme. Mutations in the gene encoding LMBR1 is the cause of several rare conditions such as acheiropody (ACHP) and syndactyly type 4 (SDYT4). ACHP is an autosomal recessive inherited disorder characterized by bilateral congenital amputations of the hands and feet. LMBR1L (limb region 1 protein homolog-like), also known as LIMR (Lipocalin-1-interacting membrane receptor), is a 489 amino acid multi-pass membrane protein that is thought to act as a receptor for Lipocalin-1 and may also assist in its endocytosis.
UOM:  1 * 100 µl
Fournisseur:  Tonbo Biosciences
Description:   The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
Fournisseur:  Apollo Scientific
Description:   Has been used as a reagent for the protection of OH-groups in oligonucleotide synthesis. A study of various cleavage methods showed that the tetramethylguanidine salts of either 4-nitrobenzaldoxime or pyridine-2-carboxaldoxime gave the best results: Tetrahedron Lett., 2727 (1978).
Fournisseur:  Avantor
Description:   La qualité de nombreux réactifs BAKER ANALYZED™ satisfait ou dépasse les exigences définies par l'American Chemical Society (ACS).
Fournisseur:  Thermo Scientific
Description:   Manganèse (II) chlorure tétrahydraté 98.0-101.0% ACS
Fournisseur:  VWR Chemicals
Description:   La gamme des étalons pour la densité relative est certifiée conforme à la méthode primaire ASTM D1480; elle dispose aussi d'une double certification conforme aux normes internationales ISO 17025 et ISO 17034 dans le cadre de l'accréditation UKAS. Les étalons de densité relative sont conçus pour l'étalonnage ou la vérification d'instruments destinés à mesurer la densité et la densité relative de matériaux à une température de test donnée, comprise entre 15 et 25 °C.
Fournisseur:  HAVER & BOECKER
Description:   Le réducteur d'échantillons rotatif HAVER produit des quantités d'échantillons de solides et de suspensions petites mais représentatives. Il combine trois méthodes de division en une unité et permet d'obtenir une précision de 99,9%.
New Product
Numéro de catalogue: (70-0037-U100)

Fournisseur:  Tonbo Biosciences
Description:   The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
UOM:  1 * 1 EA

Fournisseur:  Bioss
Description:   FRAT1 and FRAT2 were originally characterized as proteins frequently rearranged in advanced T cell lymphoma, and they have since been identified as proto-oncogenes involved in tumorigenesis. These proteins share significant homology with the Xenopus glycogen synthase kinase-3 (xGSK-3) binding protein, which is designated GBP and is essential for the formation of the dorsal-ventral axis during embryonic development. Establishment of these embryonic axes is mediated by the Wnt intracellular signaling pathway. Wnt signaling is regulated in part by the activity of GSK-3, which phosphorylates and thereby facilitates the degradation of ?catenin. GBP binds to GSK-3 and inhibits this phosphorylation, resulting in the accumulation of ?catenin and the subsequent transcription of Wnt target genes. Like GBP, FRAT2 has been shown to bind xGSK-3, suggesting that FRAT1 and FRAT2 may be GSK-3 regulatory proteins.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12434R-A647)

Fournisseur:  Bioss
Description:   FRAT1 and FRAT2 were originally characterized as proteins frequently rearranged in advanced T cell lymphoma, and they have since been identified as proto-oncogenes involved in tumorigenesis. These proteins share significant homology with the Xenopus glycogen synthase kinase-3 (xGSK-3) binding protein, which is designated GBP and is essential for the formation of the dorsal-ventral axis during embryonic development. Establishment of these embryonic axes is mediated by the Wnt intracellular signaling pathway. Wnt signaling is regulated in part by the activity of GSK-3, which phosphorylates and thereby facilitates the degradation of ?catenin. GBP binds to GSK-3 and inhibits this phosphorylation, resulting in the accumulation of ?catenin and the subsequent transcription of Wnt target genes. Like GBP, FRAT2 has been shown to bind xGSK-3, suggesting that FRAT1 and FRAT2 may be GSK-3 regulatory proteins.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-9261R-A647)

Fournisseur:  Bioss
Description:   The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF185 (ring finger protein 185), also known as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative splicing, and the gene encoding RNF185 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0637R-A750)

Fournisseur:  Bioss
Description:   The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0637R-CY5.5)

Fournisseur:  Bioss
Description:   The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
UOM:  1 * 100 µl
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