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Masterflex+Single-use+Flow+Sensor
Numéro de catalogue:
(BOSSBS-5453R-FITC)
Fournisseur:
Bioss
Description:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
UOM:
1 * 100 µl
Fournisseur:
SELENOZYME
Description:
The TrxR enzyme in C. elegans is the single selenoprotein in this organism, exerting a wide range of functions in redox control and for antioxidant systems. It is also together with glutathione reductase essential for the molting process.
We provide the main isoform of the C. elegans TrxR enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.
Numéro de catalogue:
(90097.)
Fournisseur:
Biotium
Description:
6-TAMRA SE (full name: 6-Carboxytetramethylrhodamine succinimidyl ester) is the amine-reactive form of Amine-reactive form of Carboxytetramethylrhodamine (TAMRA) single isomer. Supplied at 90 mg/mL (0.17 M) in anhydrous DMSO. The solution is suitable for labeling oligonucleotides.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0787R-HRP)
Fournisseur:
Bioss
Description:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5009R-A488)
Fournisseur:
Bioss
Description:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5009R-CY5)
Fournisseur:
Bioss
Description:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0787R-A647)
Fournisseur:
Bioss
Description:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3889R-A555)
Fournisseur:
Bioss
Description:
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9252R-A680)
Fournisseur:
Bioss
Description:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF130 (ring finger protein 130), also known as GP, G1RZFP (G1-related zinc finger protein) or GOLIATH, is a 419 amino acid single-pass type I membrane protein that shares similarity with a Drosophila zinc-finger protein found in mesoderm known as g1. RNF130 contains one PA (protease associated) domain and a single RING-type zinc finger. Implicated in the regulation of growth factor withdrawal-induced apoptosis of myeloid precursor cells, RNF130 is encoded by a gene located on human chromosome 5q35.3 and mouse chromosome 11 B1.3.
UOM:
1 * 100 µl
Fournisseur:
Tecan
Description:
The Infinite 200 PRO plate reader family offers affordable detection solutions empowered by monochromator- or filter based optics.
Numéro de catalogue:
(BTIUBNUM0451-50)
Fournisseur:
Biotium
Description:
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
UOM:
1 * 50 µl
Numéro de catalogue:
(BOSSBS-5179R)
Fournisseur:
Bioss
Description:
Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2526R-A350)
Fournisseur:
Bioss
Description:
CD160, a 27 kDa glycoprotein, was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine rich, glycosylphosphatidylinositol anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5179R-CY7)
Fournisseur:
Bioss
Description:
Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5175R)
Fournisseur:
Bioss
Description:
Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(516-1085)
Fournisseur:
Cytiva (Formerly Pall Lab)
Description:
Dispositifs et système TFF réutilisables pour les applications de biotraitement qui accélèrent et simplifient le traitement jusqu'à 1 L.
UOM:
1 * 1 ST
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