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Masterflex+Single-use+Flow+Sensor
Fournisseur:
VWR Collection
Description:
Our VWR® laboratory-grade water purification systems feature an inspiring, application-oriented design. Perform your workflows faster and more reliably, simplifying your daily lab work while ensuring cost-efficient operation over the long term. All instruments offer flexible solutions as they can be adapted to your requirements and integrated into your laboratory environment.
Fournisseur:
Endress+Hauser
Description:
COY8 Zero gel for oxygen sensors (cert. HE_01083_01.18), Sonde à oxygène dissous
Numéro de catalogue:
(PRSI91-678)
Fournisseur:
ProSci Inc.
Description:
High Mobility Group Protein B3 (HMGB3) belongs to the HMGB family. Members of the HMG box subfamily are thought to be have an important role in DNA replication, nucleosome assembly and transcription. HMGB3 binds preferentiallly single-stranded DNA and unwinds double stranded DNA. HMGB3 consists of 200 amino acids and is localized to the cell nucleus. It contains two HMG box DNA-binding domain. HMGB3 binds preferentially single-stranded DNA and unwinds double stranded DNA.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-9022R-CY7)
Fournisseur:
Bioss
Description:
IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn α-helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-CY3)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-CY7)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3686R-FITC)
Fournisseur:
Bioss
Description:
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes. EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. Target proteins are preferencially recognized via a LXXLAP motif.
UOM:
1 * 100 µl
Fournisseur:
VWR Collection
Description:
The ILCO 180 Premium offers optimal growth conditions for cell cultures and meets demanding requirements for best possible cell growth and maximum sample safety. This CO₂ incubator comes with a built-in, drift-free infrared CO₂ sensor that can be sterilised. Reliable decontamination is provided by the standard-compliant 180 °C hot air sterilisation routine which completely eliminates contaminants and ensures the inner chamber is completely sterilised. This model has an intuitive menu and user friendly software, also USB port for data download to USB stick and for uploading programs. It can be connected to Ethernet or Wi-Fi networks for remote control from any computer, and users can receive notifications about alarms/events via e-mail.
Numéro de catalogue:
(AATB474)
Fournisseur:
AAT BIOQUEST INC
Description:
The amine-reactive Texas Red®-X, succinimidyl ester is a superior replacement to Texas Red (Texas Red® is the trademark of Invitrogen).
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI26-356)
Fournisseur:
ProSci Inc.
Description:
UGCGL2 recognizes glycoproteins with minor folding defects. UGCGL2 reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
UOM:
1 * 50 µG
Fournisseur:
PRIMERDESIGN
Description:
Film de scellage pour microplaques, Bouchon en strip , Feuille individuelle/tapis/strip, Cap seals, Cap seals for BrightWhite 96-well plates, 8-strips
Numéro de catalogue:
(AATB16356)
Fournisseur:
AAT BIOQUEST INC
Description:
Nitric oxide (NO) is an important biological regulator involved in numbers of physiological and pathological processes.
UOM:
1 * 1 EA
New Product
Fournisseur:
HAMILTON BONADUZ
Description:
Les seringues multicanaux pour gel sont conçues des méthodologies de séquençage de l'ADN Multiplex. Elles peuvent transférer rapidement 8 ou 12 échantillons sur les gels de séquençage, plaques MICROTITER® ou membranes en nylon.
Fournisseur:
MACHEREY-NAGEL
Description:
CHROMABOND® C18 ec f is an endcapped octadecyl modified silica for a fast flow application in SPE.
Fournisseur:
Thermo Fisher Scientific
Description:
Accédez à tout ce dont vous avez besoin pour le pipetage grâce à ces kits tout inclus. Les kits GLP (Good Laboratory Pipetting, bonnes pratiques de pipetage) Finnpipette™ F2 fournissent des pipettes Finnpipette F2 durables et haute performance qui offrent un maximum de fiabilité et de confort.
Numéro de catalogue:
(PRSI30-934)
Fournisseur:
ProSci Inc.
Description:
CLMN is a single-pass type IV membrane protein. It contains 1 actin-binding domain and 2 CH (calponin-homology) domains. The exact function of CLMN remains unknown.
UOM:
1 * 50 µG
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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